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一名患有痴呆症且有异常饮食行为的老年女性因低碳水化合物饮食导致酮症酸中毒。

Ketoacidosis due to a Low-carbohydrate Diet in an Elderly Woman with Dementia and Abnormal Eating Behavior.

作者信息

Iwata Hitoshi, Tsuzuki Seiichiro, Iwata Mitsunaga, Terasawa Teruhiko

机构信息

Department of Emergency and General Internal Medicine, Fujita Health University School of Medicine, Japan.

出版信息

Intern Med. 2017 Oct 1;56(19):2671-2675. doi: 10.2169/internalmedicine.8689-16. Epub 2017 Sep 6.

Abstract

Strict restriction of carbohydrates can induce symptomatic ketoacidosis. We herein report a 76-year-old demented woman who developed ketoacidosis after 1 month of abnormal eating behavior involving selectively eating hamburger steak (estimated carbohydrate =12.7 g/day). Laboratory tests showed high-anion-gap metabolic acidosis with elevated blood ketone levels. She was successfully treated with intravenous fluids followed by oral intake of a regular diet. She remained relapse-free after correcting her eating habits. Healthcare providers should know that abnormal eating behavior in demented people can lead to an extremely-low-carbohydrate diet and cause atypical ketoacidosis unexplained by diabetes, heavy alcohol intake, or starvation conditions.

摘要

严格限制碳水化合物摄入可诱发症状性酮症酸中毒。我们在此报告一名76岁的痴呆女性,她在出现选择性进食汉堡排(估计碳水化合物摄入量为12.7克/天)的异常饮食行为1个月后发生了酮症酸中毒。实验室检查显示高阴离子间隙代谢性酸中毒,血酮水平升高。她通过静脉补液治疗成功,随后恢复正常饮食。在纠正饮食习惯后,她未再复发。医疗保健人员应了解,痴呆患者的异常饮食行为可能导致极低碳水化合物饮食,并引发非糖尿病、大量饮酒或饥饿状态所无法解释的非典型酮症酸中毒。

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本文引用的文献

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Eating Behaviors and Dietary Changes in Patients With Dementia.痴呆患者的饮食行为与饮食变化
Am J Alzheimers Dis Other Demen. 2016 Dec;31(8):706-716. doi: 10.1177/1533317516673155. Epub 2016 Oct 21.
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Severe Ketoacidosis in a Patient with an Eating Disorder.一名饮食失调患者的严重酮症酸中毒
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