Zhou WenQin, Luo LinLi
Department of Anesthesiology, West China Second University Hospital, Sichuan University.
Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education (Sichuan University), Chengdu, China.
Medicine (Baltimore). 2019 Oct;98(41):e17434. doi: 10.1097/MD.0000000000017434.
Preoperative prolonged fasting may cause starvation ketoacidosis. Herein, we report of a case of starvation ketoacidosis due to long-term fasting before surgery.
We report of a case of metabolic acidosis due to prolonged fasting in a previously healthy 44-year-old woman during a total laparoscopic hysterectomy. Hyperventilation was observed to occur when the surgery was completed. Metabolic acidosis and hypoglycemia were demonstrated by blood gas analysis of the radial artery.
Metabolic acidosis.
The patient received sodium bicarbonate and 5% glucose fluid at the end of the surgery.
The tracheal tube was successfully removed when the tidal volume of the patient returned to normal after the therapy. However, the patient suffered pulmonary edema when she was transferred to the intensive care unit (ICU). With treatments with furosemide and sodium bicarbonate, acidosis and pulmonary edema were completely corrected at 8 hours after the surgery. On the second day after the surgery, the patient suffered nausea and vomiting. Nausea and vomiting were not completely relieved on the sixth day after the operation; therefore, the patient was transferred to the Department of Gastroenterology for further therapy.
This case suggests that although the concept of enhanced recovery after surgery (ERAS) has been adopted by most physicians because of its positive outcomes, the issue of prolonged fasting still exists, and such patients may be exposed to the risk of starvation ketoacidosis.
术前长时间禁食可能导致饥饿性酮症酸中毒。在此,我们报告一例术前长期禁食导致的饥饿性酮症酸中毒病例。
我们报告一例44岁既往健康女性在全腹腔镜子宫切除术中因长时间禁食导致代谢性酸中毒的病例。手术结束时观察到患者出现过度通气。桡动脉血气分析显示存在代谢性酸中毒和低血糖。
代谢性酸中毒。
手术结束时患者接受了碳酸氢钠和5%葡萄糖液治疗。
治疗后患者潮气量恢复正常时成功拔除气管导管。然而,患者转至重症监护病房(ICU)时出现肺水肿。经呋塞米和碳酸氢钠治疗,术后8小时酸中毒和肺水肿完全纠正。术后第二天,患者出现恶心和呕吐。术后第六天恶心和呕吐仍未完全缓解;因此,患者转至消化内科进一步治疗。
该病例表明,尽管大多数医生因术后加速康复(ERAS)理念取得的积极效果而采用了这一理念,但长时间禁食问题仍然存在,此类患者可能面临饥饿性酮症酸中毒风险。