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本文引用的文献

1
Enhanced recovery after cesarean delivery.剖宫产术后的加速康复。
F1000Res. 2018 Apr 27;7. doi: 10.12688/f1000research.13895.1. eCollection 2018.
2
Pediatric non-diabetic ketoacidosis: a case-series report.小儿非糖尿病性酮症酸中毒:病例系列报告
BMC Pediatr. 2017 Dec 19;17(1):209. doi: 10.1186/s12887-017-0960-3.
3
Ketoacidosis due to a Low-carbohydrate Diet in an Elderly Woman with Dementia and Abnormal Eating Behavior.一名患有痴呆症且有异常饮食行为的老年女性因低碳水化合物饮食导致酮症酸中毒。
Intern Med. 2017 Oct 1;56(19):2671-2675. doi: 10.2169/internalmedicine.8689-16. Epub 2017 Sep 6.
4
Life-threatening ketoacidosis in a pregnant woman with psychotic disorder.一名患有精神障碍的孕妇出现危及生命的酮症酸中毒。
Obstet Med. 2016 Mar;9(1):46-9. doi: 10.1177/1753495X15621153. Epub 2015 Dec 24.
5
Patient-Centered Care--Enhanced Recovery After Surgery and Population Health Management.
AORN J. 2015 Dec;102(6):578-83. doi: 10.1016/j.aorn.2015.10.016.
6
Euglycemic ketoacidosis in pregnancy and its management: case report and review of literature.妊娠期间的正常血糖性酮症酸中毒及其管理:病例报告与文献综述
Eur J Obstet Gynecol Reprod Biol. 2013 Dec;171(2):386-7. doi: 10.1016/j.ejogrb.2013.09.034. Epub 2013 Oct 7.
7
Treatment of acute metabolic acidosis: a pathophysiologic approach.急性代谢性酸中毒的治疗:病理生理学方法。
Nat Rev Nephrol. 2012 Oct;8(10):589-601. doi: 10.1038/nrneph.2012.186. Epub 2012 Sep 4.
8
Severe ketoacidosis secondary to starvation in a frutarian patient.
Nutr Hosp. 2010 Nov-Dec;25(6):1049-52.
9
Metabolic acidosis: pathophysiology, diagnosis and management.代谢性酸中毒:病理生理学、诊断与治疗。
Nat Rev Nephrol. 2010 May;6(5):274-85. doi: 10.1038/nrneph.2010.33. Epub 2010 Mar 23.
10
Severe metabolic acidosis as a consequence of acute starvation in pregnancy.妊娠期间急性饥饿导致的严重代谢性酸中毒。
Arch Gynecol Obstet. 2009 Mar;279(3):399-400. doi: 10.1007/s00404-008-0715-3. Epub 2008 Jul 1.

术前长期禁食导致严重代谢性酸中毒:一例报告。

Preoperative prolonged fasting causes severe metabolic acidosis: A case report.

作者信息

Zhou WenQin, Luo LinLi

机构信息

Department of Anesthesiology, West China Second University Hospital, Sichuan University.

Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education (Sichuan University), Chengdu, China.

出版信息

Medicine (Baltimore). 2019 Oct;98(41):e17434. doi: 10.1097/MD.0000000000017434.

DOI:10.1097/MD.0000000000017434
PMID:31593098
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6799600/
Abstract

RATIONALE

Preoperative prolonged fasting may cause starvation ketoacidosis. Herein, we report of a case of starvation ketoacidosis due to long-term fasting before surgery.

PATIENT CONCERNS

We report of a case of metabolic acidosis due to prolonged fasting in a previously healthy 44-year-old woman during a total laparoscopic hysterectomy. Hyperventilation was observed to occur when the surgery was completed. Metabolic acidosis and hypoglycemia were demonstrated by blood gas analysis of the radial artery.

DIAGNOSIS

Metabolic acidosis.

INTERVENTIONS

The patient received sodium bicarbonate and 5% glucose fluid at the end of the surgery.

OUTCOMES

The tracheal tube was successfully removed when the tidal volume of the patient returned to normal after the therapy. However, the patient suffered pulmonary edema when she was transferred to the intensive care unit (ICU). With treatments with furosemide and sodium bicarbonate, acidosis and pulmonary edema were completely corrected at 8 hours after the surgery. On the second day after the surgery, the patient suffered nausea and vomiting. Nausea and vomiting were not completely relieved on the sixth day after the operation; therefore, the patient was transferred to the Department of Gastroenterology for further therapy.

LESSONS

This case suggests that although the concept of enhanced recovery after surgery (ERAS) has been adopted by most physicians because of its positive outcomes, the issue of prolonged fasting still exists, and such patients may be exposed to the risk of starvation ketoacidosis.

摘要

理论依据

术前长时间禁食可能导致饥饿性酮症酸中毒。在此,我们报告一例术前长期禁食导致的饥饿性酮症酸中毒病例。

患者情况

我们报告一例44岁既往健康女性在全腹腔镜子宫切除术中因长时间禁食导致代谢性酸中毒的病例。手术结束时观察到患者出现过度通气。桡动脉血气分析显示存在代谢性酸中毒和低血糖。

诊断

代谢性酸中毒。

干预措施

手术结束时患者接受了碳酸氢钠和5%葡萄糖液治疗。

结果

治疗后患者潮气量恢复正常时成功拔除气管导管。然而,患者转至重症监护病房(ICU)时出现肺水肿。经呋塞米和碳酸氢钠治疗,术后8小时酸中毒和肺水肿完全纠正。术后第二天,患者出现恶心和呕吐。术后第六天恶心和呕吐仍未完全缓解;因此,患者转至消化内科进一步治疗。

经验教训

该病例表明,尽管大多数医生因术后加速康复(ERAS)理念取得的积极效果而采用了这一理念,但长时间禁食问题仍然存在,此类患者可能面临饥饿性酮症酸中毒风险。