Suzuki Tomoharu, Tokuda Yasuharu, Kobayashi Hiroyuki
Department of Medicine, University of Tsukuba Mito Medical Center, Japan.
Japan Community Healthcare Organization Hospitals, Japan.
Intern Med. 2017 Oct 1;56(19):2667-2669. doi: 10.2169/internalmedicine.8769-16. Epub 2017 Sep 6.
Yellow nail syndrome (YNS) is characterized by yellowish nails, lymphedema, sinusitis, and pulmonary involvement and can be triggered by various underlying conditions, such as sinusitis or titanium exposure from an artificial joint or dental implant. Since YNS is potentially treatable, its timely diagnosis is important. The authors recently experienced a case of YNS in a patient who developed sinusitis, yellowish nails, bilateral edema of the extremities, and subclinical rheumatoid arthritis after the implantation of a cardiac pacemaker made from titanium. This case may be the first report of YNS induced by a titanium cardiac pacemaker.
黄甲综合征（YNS）的特征为指甲发黄、淋巴水肿、鼻窦炎和肺部受累，可由多种潜在疾病引发，如鼻窦炎或人工关节或牙科植入物的钛暴露。由于YNS有潜在的可治疗性，其及时诊断很重要。作者最近遇到一例YNS患者，该患者在植入钛制心脏起搏器后出现了鼻窦炎、指甲发黄、双下肢水肿和亚临床类风湿关节炎。该病例可能是钛制心脏起搏器诱发YNS的首例报告。
