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2型糖尿病中的运动训练与心脏自主神经功能:一项系统综述。

Exercise training and cardiac autonomic function in type 2 diabetes mellitus: A systematic review.

作者信息

Bhati Pooja, Shenoy Shweta, Hussain M Ejaz

机构信息

DiabetResearch Group, Centre for Physiotherapy and Rehabilitation Sciences, Jamia Millia Islamia (A Central University), New Delhi, India.

出版信息

Diabetes Metab Syndr. 2018 Jan-Mar;12(1):69-78. doi: 10.1016/j.dsx.2017.08.015. Epub 2017 Sep 6.

DOI:10.1016/j.dsx.2017.08.015
PMID:28888482
Abstract

Cardiac autonomic neuropathy (CAN) is a common complication of type 2 diabetes mellitus (T2DM). It has been found to independently predict all cause and cardiovascular disease (CVD) mortality. It remains unclear whether exercise training could improve autonomic control in T2DM patients. The purpose of this study was to systematically review the effects of exercise training on cardiac autonomic function in T2DM patients. Electronic databases (MEDLINE, CENTRAL, PEDro, Scopus and Web of science) were systematically searched to retrieve relevant evidence. Clinical trials administering exercise training for at least 4 weeks and examining either heart rate variability (HRV), baroreflex sensitivity (BRS), heart rate recovery (HRR) as outcome measures were eligible. Eighteen articles were found to be relevant and were then assessed for characteristics and quality. Fifteen studies out of 18 found that exercise training leads to positive improvements in autonomic function of T2DM patients. Exercise participation enhances cardiac autonomic function of type 2 diabetics and therefore should be implemented in their management programs.

摘要

心脏自主神经病变(CAN)是2型糖尿病(T2DM)的常见并发症。研究发现它能独立预测全因死亡率和心血管疾病(CVD)死亡率。运动训练是否能改善T2DM患者的自主神经控制尚不清楚。本研究的目的是系统评价运动训练对T2DM患者心脏自主神经功能的影响。系统检索电子数据库(MEDLINE、CENTRAL、PEDro、Scopus和科学网)以获取相关证据。至少进行4周运动训练并将心率变异性(HRV)、压力反射敏感性(BRS)、心率恢复(HRR)作为结局指标进行检测的临床试验符合要求。共发现18篇相关文章,随后对其特征和质量进行评估。18项研究中的15项发现运动训练能使T2DM患者的自主神经功能得到积极改善。运动参与可增强2型糖尿病患者的心脏自主神经功能,因此应将其纳入他们的管理方案中。

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