Department of Rehabilitation Sciences Physiotherapy, Ghent University, Ghent, Belgium; Department of Physiotherapy, Bayero University Kano, Kano State, Nigeria.
Department of Respiratory Medicine, Ghent University, Ghent, Belgium.
Physiotherapy. 2018 Mar;104(1):36-45. doi: 10.1016/j.physio.2017.07.004. Epub 2017 Jul 22.
To assess evidence for the effectiveness of aerobic exercise training (AET) on the autonomic function (AF) outcomes in patients with chronic obstructive pulmonary disease (COPD).
Online databases of PubMed, CINAHL and Web of Science were systematically searched for all years till 26th of January, 2017.
Clinical studies assessing any measure of AF following exercise training in patients with COPD were included.
Data were extracted from studies with high methodological quality for evidence synthesis. Rating of evidence quality was determined using the GRADE guidelines.
The Majority of the included studies utilized continuous exercise training mode with a vigorous level of intensity. Each exercise training session lasted between 30 to 40minutes, and the frequency of intervention was ≥3 times/week. Evidence synthesis of studies with high methodological quality revealed that a high quality evidence level supported a significant increase for time-domain heart rate variability (HRV) analyses and the heart rate recovery (HRR) following AET. The review also found that frequency domain HRV analyses were not significantly affected by AET. The evidence to support the effect of exercise training on baroreceptor sensitivity (BRS) in patients with COPD is very low.
Aerobic exercise training demonstrated beneficial but limited effects on the AF in COPD. Presently, it is not clear whether these effects are sustained in the long term. Only a limited number of RCTs were available indicating a significant gap in the literature.
评估有氧运动训练（AET）对慢性阻塞性肺疾病（COPD）患者自主神经功能（AF）结局的有效性证据。
系统检索了 PubMed、CINAHL 和 Web of Science 在线数据库中所有年份至 2017 年 1 月 26 日的文献。
纳入了评估 COPD 患者运动训练后任何 AF 测量指标的临床研究。
从具有高质量方法学证据综合的研究中提取数据。使用 GRADE 指南确定证据质量等级。
大多数纳入的研究采用了剧烈强度的连续运动训练模式。每次运动训练持续 30 至 40 分钟，干预频率≥每周 3 次。对具有高质量方法学的研究进行证据综合表明，高质量证据水平支持 AET 后时间域心率变异性（HRV）分析和心率恢复（HRR）显著增加。该综述还发现，频域 HRV 分析不受 AET 的显著影响。支持 COPD 患者运动训练对压力感受器敏感性（BRS）影响的证据非常有限。
有氧运动训练对 COPD 的 AF 具有有益但有限的影响。目前尚不清楚这些影响是否在长期内持续存在。仅有有限数量的 RCT 表明文献中存在显著差距。
