来自墨西哥阿瓜斯卡连特斯州和萨卡特卡斯州的两种响尾蛇及一个杂交种群（C. lepidus x aquilus）毒液的一般特征
General characterization of the venoms from two species of rattlesnakes and an intergrade population (C. lepidus x aquilus) from Aguascalientes and Zacatecas, Mexico.
作者信息
Rivas Eric, Neri-Castro Edgar, Bénard-Valle Melisa, Hernánez-Dávila Arely I, Zamudio F, Alagón Alejandro
机构信息
Universidad Autónoma de Aguascalientes, Av. Universidad 940, Ciudad Universitaria, Aguascalientes, Aguascalientes, 20131, Mexico.
Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad 2001, Colonia Chamilpa, Cuernavaca, Morelos, 62210, Mexico.
出版信息
Toxicon. 2017 Nov;138:191-195. doi: 10.1016/j.toxicon.2017.09.002. Epub 2017 Sep 8.
The venoms from two species of rock rattlesnakes and an intergrade population were studied. Differences were noted in SDS-PAGE and RP-HPLC profiles and only the venom from the intergrade population showed low procoagulant activity. Also, a Crotoxin-like neurotoxic PLA was identified in the venom of C. l. klauberi, the most toxic of the analyzed venoms. This is the first report of such a toxin in C. l. klauberi from Aguascalientes, Mexico.
对两种岩响尾蛇的毒液以及一个过渡种群的毒液进行了研究。在SDS-PAGE和RP-HPLC图谱中发现了差异，只有过渡种群的毒液显示出较低的促凝血活性。此外，在被分析的毒性最强的C. l. klauberi毒液中鉴定出了一种类响尾蛇毒素神经毒性磷脂酶A。这是来自墨西哥阿瓜斯卡连特斯的C. l. klauberi中首次报道此类毒素。
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