Chen Chao, Kong Fanxing, Wei Xiaohu, Thang San H
Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.
Chem Commun (Camb). 2017 Sep 28;53(78):10776-10779. doi: 10.1039/c7cc05316a.
In this study, a series of functional peptide-based RAFT agents were designed and synthesized by the solid-phase supported peptide synthesis method. These novel RAFT agents have enabled chemists to make well-defined peptide-polymer conjugates with complicated topological structures. Additionally, our results have shown an unexpected reaction that takes place during these syntheses, and the conversion of a nitrile group to a carboxamide group has been evidently elucidated and unambiguously confirmed.
