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西伯利亚杏叶中的抗氧化酚酸

Antioxidant phenolic acids from the leaves of Armeniaca sibirica.

作者信息

Wu Ya-Nan, Wang Wei, Yao Guo-Dong, Jiang Xue-Feng, Zhang Yan, Song Shao-Jiang

机构信息

a School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang 110016 , China.

b Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education , Shenyang Pharmaceutical University , Shenyang 110016 , China.

出版信息

J Asian Nat Prod Res. 2018 Oct;20(10):969-976. doi: 10.1080/10286020.2017.1373101. Epub 2017 Sep 11.

Abstract

Phytochemical investigation of the leaves of Armeniaca sibirica (L.) Lam. led to the isolation of two new phenolic acids (1-2), together with eight known compounds (3-10) from the ethanol extracts of this plant. Structures of these compounds were elucidated through detailed spectroscopic analyses, using 1D-NMR and 2D-NMR in combination with HR-EI-MS techniques. All the compounds were evaluated for their antioxidant capabilities in vitro using 2, 2'-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS), 1, 1'-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assays, and ferric-reducing antioxidant power (FRAP) methods.

摘要

对山杏(Armeniaca sibirica (L.) Lam.)叶片进行植物化学研究,从该植物的乙醇提取物中分离出两种新的酚酸(1 - 2)以及八种已知化合物(3 - 10)。通过详细的光谱分析,结合一维核磁共振(1D - NMR)、二维核磁共振(2D - NMR)以及高分辨电子轰击质谱(HR - EI - MS)技术阐明了这些化合物的结构。使用2,2'-联氮-双-3-乙基苯并噻唑啉-6-磺酸(ABTS)、1,1'-二苯基-2-苦基肼(DPPH)自由基清除试验以及铁离子还原抗氧化能力(FRAP)方法对所有化合物的体外抗氧化能力进行了评估。

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