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草药制剂——茶树油作为微创牙科中窝洞消毒剂辅助剂的作用——一项体内比较研究。

Role of Herbal Agents - Tea Tree Oil and as Cavity Disinfectant Adjuncts in Minimally Invasive Dentistry-An In vivo Comparative Study.

作者信息

Patri Gaurav, Sahu Aliva

机构信息

Professor, Department of Conservative Dentistry and Endodontics, Kalinga Institute of Dental Sciences/KIIT University, Bhubaneswar, Odisha, India.

Postgraduate Student, Department of Conservative Dentistry and Endodontics, Kalinga Institute of Dental Sciences/KIIT University, Bhubaneswar, Odisha, India.

出版信息

J Clin Diagn Res. 2017 Jul;11(7):DC05-DC09. doi: 10.7860/JCDR/2017/27598.10147. Epub 2017 Jul 1.

DOI:10.7860/JCDR/2017/27598.10147
PMID:28892888
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5583794/
Abstract

INTRODUCTION

The prevention and control of caries necessitates the elimination of cariogenic bacteria and cavity disinfectants have proved to play a major role in achieving the goal. The use of phytotherapy is trending and many natural products have shown anti-microbial properties which can be used as cavity disinfectant in the field of dentistry.

AIM

The aim of this study was to compare the efficacy of herbal antibacterial agents (Tea Tree Oil (TTO) and ) with commercially available 2% chlorhexidine (CHX) as cavity disinfectant for use in minimally invasive dentistry.

MATERIALS AND METHODS

The study included three test groups, Group I (2% chlorhexidine), Group II (tea tree oil), Group III ( gel) with a control group (distilled water). Ten patients with atleast one tooth with an occlusal or occluso-proximal lesion suitable for Atraumatic Restorative Treatment (ART) were selected for each group, dentinal samples were collected using sterile spoon excavators at three stages from each tooth viz., pre-excavation, post-excavation and post-disinfection of the cavities. These dentinal samples were subjected to microbiological analysis for Total Viable Count (TVC). The data collected were statistically analysed using ANOVA and Bonferroni post-hoc test.

RESULTS

The results of present study showed that there was a statistically significant reduction in TVC when compared between pre and post excavation in all the groups (p<0.05) and post- excavation and post-disinfection in all the test groups (p<0.05) (except control group). Post-disinfection, 2% chlorhexidine showed highest reduction in TVC followed by 1% tea tree oil and aloe vera gel.

CONCLUSION

Natural antibacterial agents like tea tree oil and aloe vera could be effectively used as cavity disinfectants which will help in minimizing secondary caries and rendering a long term restorative success.

摘要

引言

龋齿的预防和控制需要消除致龋菌,而窝洞消毒剂已被证明在实现这一目标中发挥着重要作用。植物疗法正呈流行趋势,许多天然产物已显示出抗菌特性,可在牙科领域用作窝洞消毒剂。

目的

本研究的目的是比较草药抗菌剂(茶树油(TTO)和芦荟凝胶)与市售2%氯己定(CHX)作为微创牙科中窝洞消毒剂的疗效。

材料和方法

该研究包括三个试验组,第一组(2%氯己定),第二组(茶树油),第三组(芦荟凝胶),另有一个对照组(蒸馏水)。每组选择10名至少有一颗适合非创伤性修复治疗(ART)的咬合面或咬合邻面病变牙齿的患者,使用无菌匙形挖器在每个牙齿的三个阶段(即窝洞挖掘前、挖掘后和消毒后)收集牙本质样本。这些牙本质样本进行了总活菌数(TVC)的微生物分析。收集的数据使用方差分析和Bonferroni事后检验进行统计分析。

结果

本研究结果表明,所有组在挖掘前和挖掘后相比,TVC均有统计学显著降低(p<0.05),所有试验组在挖掘后和消毒后相比(对照组除外)TVC也有统计学显著降低(p<0.05)。消毒后,2%氯己定的TVC降低最多,其次是1%茶树油和芦荟凝胶。

结论

茶树油和芦荟等天然抗菌剂可有效用作窝洞消毒剂,这将有助于减少继发龋并实现长期修复成功。

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