Kutiyal Aditya Singh, Malik Chetanya, Hyanki Gitika
Senior Resident, Department of Internal Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Postgraduate Resident, Department of Pathology, Government Medical College, Haldwani, Uttarakhand, India.
J Clin Diagn Res. 2017 Jul;11(7):OD10-OD12. doi: 10.7860/JCDR/2017/28814.10243. Epub 2017 Jul 1.
Dengue is an endemic arboviral infection prevalent especially in tropical countries including Southern and Southeast Asia. Central Nervous System (CNS) involvement in dengue infection is uncommon. Haemorrhagic encephalitis is a rare presentation in dengue. This is a case of a 58-year-old male who presented with fever, petechial rash and altered sensorium. Dengue serology IgM was reactive and MRI brain was suggestive of haemorrhagic encephalitis. Patient was managed in Intensive Care Unit (ICU) but eventually succumbed to his illness. We report this fatal outcome of a common viral infection with unusual neurological presentation to propose an association between dengue and neurotropism and the need to look at dengue infection beyond its classical features.
登革热是一种地方性虫媒病毒感染,尤其在包括南亚和东南亚在内的热带国家流行。登革热感染累及中枢神经系统(CNS)的情况并不常见。出血性脑炎是登革热中一种罕见的表现形式。这是一例58岁男性患者,表现为发热、瘀点皮疹和意识改变。登革热血清学IgM呈阳性反应,脑部磁共振成像(MRI)提示出血性脑炎。患者在重症监护病房(ICU)接受治疗,但最终因病死亡。我们报告了这种常见病毒感染导致的致命结果,其具有不寻常的神经学表现,旨在提出登革热与嗜神经性之间的关联,以及除了其经典特征外还需关注登革热感染的必要性。