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本文引用的文献

1
Squamous cell carcinoma of submandibular salivary gland: A rare case report.下颌下涎腺鳞状细胞癌:1例罕见病例报告
J Oral Maxillofac Pathol. 2014 May;18(2):299-302. doi: 10.4103/0973-029X.140909.
2
Systemic therapy in the management of metastatic or advanced salivary gland cancers.转移性或晚期唾液腺癌治疗中的全身治疗
Head Neck Oncol. 2012 May 4;4:19. doi: 10.1186/1758-3284-4-19.
3
Current role of chemotherapy in exclusive and integrated treatment of malignant tumours of salivary glands.化疗在唾液腺恶性肿瘤单纯治疗与综合治疗中的当前作用。
Acta Otorhinolaryngol Ital. 2005 Jun;25(3):179-81.
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Management and outcome of patients with malignant salivary gland tumors.恶性唾液腺肿瘤患者的管理与预后
J Oral Maxillofac Surg. 2005 Jul;63(7):917-28. doi: 10.1016/j.joms.2005.03.006.
5
Salivary gland tumours.唾液腺肿瘤
Oral Dis. 2002 Sep;8(5):229-40. doi: 10.1034/j.1601-0825.2002.02870.x.
6
Squamous carcinoma in a major salivary gland: a review of the diagnostic considerations.大唾液腺鳞状细胞癌:诊断考量综述
Arch Pathol Lab Med. 2001 Jun;125(6):740-5. doi: 10.5858/2001-125-0740-SCIAMS.
7
Primary squamous cell carcinoma of the parotid gland: the importance of correct histological diagnosis.腮腺原发性鳞状细胞癌:正确组织学诊断的重要性。
Ann Surg Oncol. 1999 Dec;6(8):768-70. doi: 10.1007/s10434-999-0768-y.

下颌下唾液腺原发性鳞状细胞癌:一例报告

Primary Squamous Cell Carcinoma of Submandibular Salivary Gland: A Case Report.

作者信息

Agarwal Manmohan, Agarwal Lakshmi, Saxena Rajeev

机构信息

Consultant, Department of Oncosurgery, Pushpadi Cancer Care Center, Kota, Rajasthan, India.

Assistant Professor, Department of Pathology, Govt. Medical College, Kota, Rajasthan, India.

出版信息

J Clin Diagn Res. 2017 Jul;11(7):XD01-XD02. doi: 10.7860/JCDR/2017/26356.10158. Epub 2017 Jul 1.

DOI:10.7860/JCDR/2017/26356.10158
PMID:28893025
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5583916/
Abstract

Primary Squamous Cell Carcinoma (PSCC) of submandibular salivary gland is a rare occurrence. Careful clinical and histopathological examination is must to diagnose it. The treatment protocol of this rare disease is not clearly defined. Though surgery is primary treatment, role of adjuvant treatment is not clear. A 40-year-old male presented to us with asymptomatic upper neck swelling. Triple endoscopy, cross-sectional investigation and FNAC suggested primary squamous cell carcinoma of right submandibular salivary gland. He was treated with bilateral modified neck dissection and wide excision of sub mandibular gland with surrounding muscles. Post surgery, he had undergone interval chemotherapy followed by radiotherapy. The patient is still on regular follow up at an interval of three months without any evidence of disease recurrence. Though difficult to diagnose and treat this kind of rare variant of salivary neoplasms, awareness of the disease and aggressive treatment depending on histopathology report, can help patient to achieve health.

摘要

下颌下唾液腺原发性鳞状细胞癌(PSCC)较为罕见。必须进行仔细的临床和组织病理学检查以诊断该病。这种罕见疾病的治疗方案尚未明确界定。虽然手术是主要治疗方法,但辅助治疗的作用尚不明确。一名40岁男性因无症状的上颈部肿胀前来就诊。三联内镜检查、横断面检查和细针穿刺抽吸活检提示右下颌下唾液腺原发性鳞状细胞癌。他接受了双侧改良颈清扫术以及下颌下腺连同周围肌肉的广泛切除术。术后,他接受了间歇化疗,随后进行了放疗。该患者仍每三个月定期随访,无疾病复发迹象。尽管诊断和治疗这种罕见的唾液腺肿瘤变体很困难,但对该疾病的认识以及根据组织病理学报告进行积极治疗,有助于患者恢复健康。