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下颌下唾液腺原发性鳞状细胞癌:一例报告

Primary Squamous Cell Carcinoma of Submandibular Salivary Gland: A Case Report.

作者信息

Agarwal Manmohan, Agarwal Lakshmi, Saxena Rajeev

机构信息

Consultant, Department of Oncosurgery, Pushpadi Cancer Care Center, Kota, Rajasthan, India.

Assistant Professor, Department of Pathology, Govt. Medical College, Kota, Rajasthan, India.

出版信息

J Clin Diagn Res. 2017 Jul;11(7):XD01-XD02. doi: 10.7860/JCDR/2017/26356.10158. Epub 2017 Jul 1.

Abstract

Primary Squamous Cell Carcinoma (PSCC) of submandibular salivary gland is a rare occurrence. Careful clinical and histopathological examination is must to diagnose it. The treatment protocol of this rare disease is not clearly defined. Though surgery is primary treatment, role of adjuvant treatment is not clear. A 40-year-old male presented to us with asymptomatic upper neck swelling. Triple endoscopy, cross-sectional investigation and FNAC suggested primary squamous cell carcinoma of right submandibular salivary gland. He was treated with bilateral modified neck dissection and wide excision of sub mandibular gland with surrounding muscles. Post surgery, he had undergone interval chemotherapy followed by radiotherapy. The patient is still on regular follow up at an interval of three months without any evidence of disease recurrence. Though difficult to diagnose and treat this kind of rare variant of salivary neoplasms, awareness of the disease and aggressive treatment depending on histopathology report, can help patient to achieve health.

摘要

下颌下唾液腺原发性鳞状细胞癌(PSCC)较为罕见。必须进行仔细的临床和组织病理学检查以诊断该病。这种罕见疾病的治疗方案尚未明确界定。虽然手术是主要治疗方法,但辅助治疗的作用尚不明确。一名40岁男性因无症状的上颈部肿胀前来就诊。三联内镜检查、横断面检查和细针穿刺抽吸活检提示右下颌下唾液腺原发性鳞状细胞癌。他接受了双侧改良颈清扫术以及下颌下腺连同周围肌肉的广泛切除术。术后,他接受了间歇化疗,随后进行了放疗。该患者仍每三个月定期随访,无疾病复发迹象。尽管诊断和治疗这种罕见的唾液腺肿瘤变体很困难,但对该疾病的认识以及根据组织病理学报告进行积极治疗,有助于患者恢复健康。

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