形态发生：通过细胞外力梯度塑造组织。

Morphogenesis: Shaping Tissues through Extracellular Force Gradients.

机构信息

Department of Biology, Regeneration Next, Duke University, Durham, NC, USA.

出版信息

Curr Biol. 2017 Sep 11;27(17):R850-R852. doi: 10.1016/j.cub.2017.07.040.

DOI:10.1016/j.cub.2017.07.040

Abstract

Organ sculpting requires directed physical force generation. Force imbalances are primarily thought to arise from within cells. A new study, however, demonstrates that an extracellular-matrix-based stiffness gradient in the Drosophila egg chamber instructs tissue elongation.

摘要

器官塑形需要定向的物理力生成。力的失衡主要被认为是由细胞内部引起的。然而，一项新的研究表明，果蝇卵室中基于细胞外基质的硬度梯度指导组织伸长。