Erjaee Asma, Niknam Maryam, Sadeghi Ahmadreza, Dehghani Maryam, Safaei Zeinab, Teshnizi Saeed Hosseini, Karimi Mehran
Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Pediatrics, Shiraz University of Medical Sciences, Shiraz, Iran.
Indian J Med Paediatr Oncol. 2017 Apr-Jun;38(2):158-164. doi: 10.4103/ijmpo.ijmpo_40_16.
This study investigates epidemiologic and practical information about the incidence and risk factors of childhood cancer in a population of Southern Iranian children.
A total number of 300 cancer patients along with 600 age- and gender-matched healthy control were interviewed by a trained physician regarding their demographic characteristics, and major family-associated risk factors, childhood malignancies.
The average annual percentage change for cancers in the studied population is calculated as 45%. Our study indicated that possible risk factors which could contribute to the development of childhood cancer are maternal oral contraceptive pill use during pregnancy, exposure to radiation during pregnancy, parental smoking, residence near high voltage electricity lines, exposure to pesticides and fertilizers, patient allergy, contact with domestic animals and father's educational degree. Furthermore, new ecological risk factors such as air pollution due to nonstandard petroleum or toxic inhalant particles, nonhealthy food consumption, and satellite jamming are other predisposing factors.
Our study reported a higher average annual percentage change of childhood cancers in our area, compared to the existing literature. In conclusion, detection and prevention of the consistent and possible new environmental risk factors such as nonstandard petroleum or satellite jamming from all around the country should be taking into consideration.
本研究调查了伊朗南部儿童群体中儿童癌症发病率及危险因素的流行病学和实际信息。
由一名经过培训的医生对300名癌症患儿及600名年龄和性别匹配的健康对照者进行访谈,了解他们的人口统计学特征、主要的家庭相关危险因素以及儿童恶性肿瘤情况。
研究人群中癌症的年均变化率计算为45%。我们的研究表明,可能导致儿童癌症发生的危险因素包括母亲孕期服用口服避孕药、孕期接触辐射、父母吸烟、居住在高压电线附近、接触农药和化肥、患儿过敏、接触家畜以及父亲的教育程度。此外,新的生态危险因素,如因不标准石油或有毒吸入颗粒导致的空气污染、不健康的食物消费以及卫星干扰,也是其他诱发因素。
与现有文献相比,我们的研究报告了本地区儿童癌症更高的年均变化率。总之,应考虑检测和预防来自全国各地的持续存在的以及可能的新环境危险因素,如不标准石油或卫星干扰。