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基于人群的芬兰研究中季节性情感障碍和酗酒对睡眠和打鼾功能的影响。

The effects of seasonal affective disorder and alcohol abuse on sleep and snoring functions in a population-based study in Finland.

机构信息

Department of Health, National Institute for Health and Welfare, Helsinki, Finland.

出版信息

J Sleep Res. 2018 Aug;27(4):e12611. doi: 10.1111/jsr.12611. Epub 2017 Sep 13.

Abstract

Seasonal affective disorder (SAD) is a recurrent depressive disorder with a seasonal pattern. In addition to some specific symptoms such as sad mood, low energy or carbohydrate craving, this mood disorder is also characterized by the presence of sleeping problems and alcohol disorders. Interestingly, there is a strong link between alcohol use and sleeping deficits. Although previous studies have focused extensively on the sleep patterns in SAD patients and patients with alcohol use disorder (AUD), no research has yet been conducted on subjects with comorbid SAD and AUD. The aim of this study was to examine the differences in sleep functioning between subjects with SAD, AUD and SAD+AUD. A total of 4554 Finnish subjects from the population-based Health 2011 survey were interviewed, and of these 2430 individuals completed all the questionnaires. We selected those participants who fulfilled the criteria for SAD (n = 298), AUD (n = 359), SAD+AUD (n = 69), controls 1 (no current alcohol use, n = 226) and controls 2 (current alcohol use but not AUD, n = 1445). Controls with a history of alcohol abuse were excluded (n = 33). All the participants completed the EuroQoL five-dimensions questionnaire (EQ-5), the Seasonal Pattern Assessment Questionnaire (SPAQ), the Alcohol Use Disorders Identification Test (AUDIT) and several questions about sleeping, based on the Basic Nordic Sleep Questionnaire (BNSQ). Our results showed that those subjects with SAD+AUD reported the highest levels of subjective sleeping problems compared to controls, SAD and AUD. These findings suggest the relevance of examining the comorbidity of SAD and AUD when studying sleep functioning in these groups of patients.

摘要

季节性情感障碍(SAD)是一种具有季节性模式的复发性抑郁障碍。除了情绪低落、精力不足或渴望碳水化合物等一些特定症状外,这种情绪障碍还表现为睡眠问题和酒精障碍。有趣的是,饮酒和睡眠不足之间存在很强的联系。尽管先前的研究广泛关注 SAD 患者和酒精使用障碍(AUD)患者的睡眠模式,但尚未对同时患有 SAD 和 AUD 的患者进行研究。本研究旨在探讨 SAD、AUD 和 SAD+AUD 患者睡眠功能的差异。该研究共对来自芬兰基于人群的 2011 年健康调查的 4554 名受试者进行了访谈,其中 2430 人完成了所有问卷。我们选择了那些符合 SAD(n=298)、AUD(n=359)、SAD+AUD(n=69)、对照组 1(无当前饮酒,n=226)和对照组 2(当前饮酒但无 AUD,n=1445)标准的参与者。排除了有酒精滥用史的对照组(n=33)。所有参与者都完成了欧洲五维健康量表(EQ-5)、季节性模式评估问卷(SPAQ)、酒精使用障碍识别测试(AUDIT)以及基于北欧基本睡眠问卷(BNSQ)的一些关于睡眠的问题。研究结果表明,与对照组、SAD 和 AUD 相比,SAD+AUD 患者报告的主观睡眠问题水平最高。这些发现表明,在研究这些患者群体的睡眠功能时,检查 SAD 和 AUD 的共病情况是很重要的。

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