温和条件下铑催化吡啶酮直接合成喹诺酮：在检测硝基芳烃中的应用。
A Mild Rhodium Catalyzed Direct Synthesis of Quinolones from Pyridones: Application in the Detection of Nitroaromatics.
机构信息
Department of Chemistry, Indian Institute of Technology Kharagpur , Kharagpur 721302, India.
出版信息
J Org Chem. 2017 Oct 20;82(20):10989-10996. doi: 10.1021/acs.joc.7b01932. Epub 2017 Sep 28.
PMID:28901761
Abstract
A rhodium catalyzed direct regioselective oxidative annulation by double C-H activation is described to synthesize highly substituted quinolones from pyridones. The reaction proceeds at mild conditions with broad scope and wide functional group tolerance. These novel quinolones were explored to recognize nitroaromatic compounds.
摘要
本文描述了一种铑催化的直接区域选择性氧化环化反应，通过双重 C-H 活化来合成高度取代的喹诺酮类化合物。该反应在温和的条件下进行，具有广泛的适用范围和广泛的官能团耐受性。这些新型的喹诺酮类化合物被探索用于识别硝基芳香族化合物。
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