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经皮神经刺激成功治疗瘙痒和特应性皮炎。

Successful treatment of itching and atopic eczema by transcutaneous nerve stimulation.

作者信息

Bjørnå H, Kaada B

机构信息

Rogaland Central Hospital, Stavanger, Norway.

出版信息

Acupunct Electrother Res. 1987;12(2):101-12. doi: 10.3727/036012987816358904.

DOI:10.3727/036012987816358904
PMID:2890272
Abstract

Low-frequency (2 Hz) transcutaneous electrical nerve stimulation (TNS) may produce prolonged and widespread sympatho-inhibition resulting in improved skin microcirculation with increased skin temperature in patients with peripheral vascular insufficiency. The method has previously been used successfully to improve peripheral circulation in such patients and to accelerate healing of chronic skin ulcers of various etiology. The present report deals with healing of atopic eczema and relief of pruritus by low-frequency TNS treatment in a patient who was followed for 2 years, the first 8 months with daily recordings of the effects, and then for an additional 16 months during which period TNS only occasionally was used. TNS also produced increased plasma levels of ACTH, cortisol and vasoactive intestinal polypeptides (VIP). The mechanisms of the favourable clinical effects are discussed.

摘要

低频(2赫兹)经皮电神经刺激(TNS)可能会产生持久且广泛的交感神经抑制,从而改善外周血管功能不全患者的皮肤微循环并提高皮肤温度。该方法此前已成功用于改善此类患者的外周循环,并加速各种病因引起的慢性皮肤溃疡的愈合。本报告涉及一名患者通过低频TNS治疗特应性皮炎的愈合情况及瘙痒缓解情况,该患者接受了2年的随访,前8个月每天记录疗效,随后的16个月期间仅偶尔使用TNS。TNS还使促肾上腺皮质激素、皮质醇和血管活性肠肽(VIP)的血浆水平升高。文中讨论了这些良好临床效果的机制。

相似文献

1
Successful treatment of itching and atopic eczema by transcutaneous nerve stimulation.经皮神经刺激成功治疗瘙痒和特应性皮炎。
Acupunct Electrother Res. 1987;12(2):101-12. doi: 10.3727/036012987816358904.
2
Successful treatment of esophageal dysmotility and Raynaud's phenomenon in systemic sclerosis and achalasia by transcutaneous nerve stimulation. Increase in plasma VIP concentration.经皮神经刺激成功治疗系统性硬化症和贲门失弛缓症中的食管运动障碍及雷诺现象。血浆血管活性肠肽浓度升高。
Scand J Gastroenterol. 1987 Nov;22(9):1137-46. doi: 10.3109/00365528708991971.
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In search of mediators of skin vasodilation induced by transcutaneous nerve stimulation: III. Increase in plasma VIP in normal subjects and in Raynaud's disease.寻找经皮神经刺激诱导的皮肤血管舒张的介质:III. 正常受试者和雷诺病患者血浆血管活性肠肽的增加
Gen Pharmacol. 1984;15(2):107-13. doi: 10.1016/0306-3623(84)90091-0.
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Promoted healing of leprous ulcers by transcutaneous nerve stimulation.经皮神经刺激促进麻风溃疡愈合。
Acupunct Electrother Res. 1988;13(4):165-76. doi: 10.3727/036012988816358589.
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Failure to influence the VIP level in the cerebrospinal fluid by transcutaneous nerve stimulation in humans.经皮神经刺激未能影响人体脑脊液中的VIP水平。
Gen Pharmacol. 1984;15(6):563-5. doi: 10.1016/0306-3623(84)90218-0.
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Transcutaneous nerve stimulation in patients with coronary arterial disease: haemodynamic and biochemical effects.
Eur Heart J. 1990 May;11(5):447-53.
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Transcutaneous nerve stimulation and itching.
Acta Derm Venereol. 1978;58(2):131-4.
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Recent studies of cutaneous nociception in atopic and non-atopic subjects.近期针对特应性和非特应性受试者皮肤痛觉的研究。
J Dermatol. 1999 Feb;26(2):77-86. doi: 10.1111/j.1346-8138.1999.tb03516.x.
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Concomitant increase in nociceptive flexion reflex threshold and plasma opioids following transcutaneous nerve stimulation.经皮神经刺激后伤害性屈曲反射阈值和血浆阿片类物质同时增加。
Pain. 1984 Jul;19(3):295-303. doi: 10.1016/0304-3959(84)90006-X.
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Use of transcutaneous electrical nerve stimulation for chronic pruritus.经皮电神经刺激在慢性瘙痒治疗中的应用。
Dermatol Ther. 2015 Jul-Aug;28(4):210-5. doi: 10.1111/dth.12242. Epub 2015 May 14.

引用本文的文献

1
Electrical neurostimulation for the treatment of chronic pruritus: A systematic review.电神经刺激治疗慢性瘙痒症:系统评价。
Exp Dermatol. 2022 Mar;31(3):280-289. doi: 10.1111/exd.14468. Epub 2021 Dec 7.
2
Transcutaneous electrical nerve stimulation decreases lower esophageal sphincter pressure in patients with achalasia.经皮电神经刺激可降低贲门失弛缓症患者的下食管括约肌压力。
Dig Dis Sci. 1991 Aug;36(8):1029-33. doi: 10.1007/BF01297442.