Wu Jih-Huah, Chang Rong-Seng, Jiang Joe-Air
Department of Biomedical Engineering, Ming Chuan University, No. 5, Deming Rd., Gweishan Township, Taoyuan 333, Taiwan.
Department of Optics and Photonics, National Central University, No. 300, Jung-Da Rd., Chung-Li City, Taoyuan 320, Taiwan.
Sensors (Basel). 2007 Dec 19;7(12):3366-3385. doi: 10.3390/s7123366.
This paper presents a novel, non-invasive, non-contact system to measure pulsewaveforms of artery via applying laser triangulation method to detect skin surfacevibration. The proposed arterial pulsation measurement (APM) system chiefly consists of alaser diode and a low cost complementary metal-oxide semiconductor (CMOS) imagesensor. Laser triangulation and centroid method are combined with the Fast FourierTransform (FFT) in this study. The shape and frequency of the arterial pulsation can bedetected rapidly by using our APM system. The relative variation of the pulse at differentmeasurement points near wrist joint is used as a prognostic guide in traditional Chinesemedicine (TCM). An extensive series of experiments was conducted to evaluate theperformance of the designed APM system. From experimental results, the pulse amplitudeand frequency at the Chun point (related to the small intestine) of left hand showed anobvious increase after having food. In these cases, the peak to peak amplitudes and thefrequencies of arterial pulsations range from 38 to 48 μm and from 1.27 to 1.35 Hz,respectively. The height of arterial pulsations on the area near wrist joint can be estimatedwith a resolution of better than 4 μm. This research demonstrates that applying a CMOSimage sensor in designing a non-contact, portable, easy-to-use, low cost pulse measurementsystem is feasible. Also, the designed APM system is well suited for evaluating and pre-diagnosing the health of a human being in TCM clinical practice.
本文提出了一种新颖的、非侵入性的、非接触式系统，通过应用激光三角测量法检测皮肤表面振动来测量动脉脉搏波形。所提出的动脉搏动测量（APM）系统主要由一个激光二极管和一个低成本的互补金属氧化物半导体（CMOS）图像传感器组成。本研究将激光三角测量法和质心法与快速傅里叶变换（FFT）相结合。使用我们的APM系统可以快速检测动脉搏动的形状和频率。在中医中，手腕关节附近不同测量点处脉搏的相对变化被用作预后指导。进行了一系列广泛的实验来评估所设计的APM系统的性能。从实验结果来看，左手寸口（与小肠相关）处的脉搏幅度和频率在进食后有明显增加。在这些情况下，动脉搏动的峰峰值幅度和频率分别在38至48μm和1.27至1.35Hz范围内。手腕关节附近区域动脉搏动的高度可以以优于4μm的分辨率进行估计。本研究表明，在设计非接触式、便携式、易于使用、低成本的脉搏测量系统中应用CMOS图像传感器是可行的。此外，所设计的APM系统非常适合在中医临床实践中评估和预诊断人体健康状况。
