Ghimire Obin, Wenzheng Li, Huaping Liu, Wenguang Liu, Yigang Pei, Jiale Hou
Department Of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China (mainland).
Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, China (mainland).
Am J Case Rep. 2017 Sep 14;18:989-994. doi: 10.12659/ajcr.903908.
BACKGROUND Angiomyolipoma is a benign tumor composed of blood vessels, smooth muscle cells, and adipose tissue and has been described as belonging to the group of tumors of perivascular epithelioid cell origin (PEComa), commonly found in the kidneys and strongly associated with tuberous sclerosis. Only a few cases of extra-renal angiomyolipoma have previously been reported in the literature, most commonly in the liver. Adrenal angiomyolipoma is very rare, is usually asymptomatic, and is often found incidentally, with only 14 previously reported cases identified in the literature. CASE REPORT We report two cases of adrenal angiomyolipoma that were identified by abdominal computed tomography (CT). The first case presented in a 36-year-old man and was an oval-shaped adrenal mass, measuring 5.2×4.2×3.1 cm. The second case presented in a 61-year-old woman and was a round-shaped mass measuring 8.6×9.5×8.1 cm. Both patients underwent adrenalectomy. Histopathology and immunohistochemistry confirmed the diagnosis of benign angiomyolipoma composed of adipose tissues, blood vessels, and smooth muscle cells. CONCLUSIONS We present two rare cases of adrenal angiomyolipoma. We have reviewed the literature and identified 14 other cases of adrenal angiomyolipoma, and discuss the clinical, radiological, and pathological features of this rare tumor.
血管平滑肌脂肪瘤是一种由血管、平滑肌细胞和脂肪组织组成的良性肿瘤，被认为属于血管周上皮样细胞来源肿瘤（PEComa）组，常见于肾脏，且与结节性硬化症密切相关。此前文献中仅报道过少数肾外血管平滑肌脂肪瘤病例，最常见于肝脏。肾上腺血管平滑肌脂肪瘤非常罕见，通常无症状，常为偶然发现，文献中仅报道过14例。病例报告：我们报告两例经腹部计算机断层扫描（CT）确诊的肾上腺血管平滑肌脂肪瘤病例。第一例为一名36岁男性，肾上腺肿块呈椭圆形，大小为5.2×4.2×3.1厘米。第二例为一名61岁女性，肿块呈圆形，大小为8.6×9.5×8.1厘米。两名患者均接受了肾上腺切除术。组织病理学和免疫组织化学证实诊断为良性血管平滑肌脂肪瘤，由脂肪组织、血管和平滑肌细胞组成。结论：我们报告了两例罕见的肾上腺血管平滑肌脂肪瘤病例。我们回顾了文献并确定了另外14例肾上腺血管平滑肌脂肪瘤病例，并讨论了这种罕见肿瘤的临床、放射学和病理学特征。
