Govindarajan Matheswari, Mallikarjunan Shanmugapriya, Ahmed Hajira S R, Lakshmanan Naveena, Silambuchelvi D, Sujatha M, Subramanian Vidyalakshmi
Department of Biotechnology, PSG College of Technology, Coimbatore, Tamil Nadu, India.
Vamsam Fertility Centre, Coimbatore, Tamil Nadu, India.
J Hum Reprod Sci. 2017 Apr-Jun;10(2):114-118. doi: 10.4103/jhrs.JHRS_3_17.
This study is aimed at determining the prognostic factors influencing successful pregnancy following intrauterine insemination (IUI).
Retrospective analysis.
A total of 2123 cycles undergone by 871 couples during the period of 5 years (2011-2015) were retrospectively studied.
Each of the factors was compared with pregnancy outcome (PO) using statistical analysis with a confidence interval of 95% in SPSS software version 19. Chi-square test and logistic regression analysis method were used to determine the significance of each factor with the PO.
Among the various factors included in our study population, male habits ( = 0.004), male occupational environment ( = 0.025), male age ( = 0.002), and female age ( = 0.001) were found to significantly influence the PO following IUI.
Our results indicate that avoiding smoking and alcohol consuming prior and during the IUI treatment along with working in low-heat-generating environment might lead to better success following the treatment.
本研究旨在确定影响宫腔内人工授精（IUI）后成功妊娠的预后因素。
回顾性分析。
回顾性研究了871对夫妇在5年期间（2011 - 2015年）共进行的2123个周期。
在SPSS 19版软件中，采用统计分析将每个因素与妊娠结局（PO）进行比较，置信区间为95%。采用卡方检验和逻辑回归分析方法确定每个因素与PO的显著性。
在我们研究人群纳入的各种因素中，发现男性习惯（P = 0.004）、男性职业环境（P = 0.025）、男性年龄（P = 0.002）和女性年龄（P = 0.001）对IUI后的PO有显著影响。
我们的结果表明，在IUI治疗前和治疗期间避免吸烟和饮酒，以及在低热量产生的环境中工作，可能会使治疗后获得更好的成功率。
