Department of Anatomical Sciences, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Department of Pediatrics, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA.
Reprod Biol Endocrinol. 2020 Nov 13;18(1):110. doi: 10.1186/s12958-020-00668-y.
Many factors, including postponement of marriage, increased life expectancy, and improved success with assisted reproductive technologies have been contributing to increased paternal age in developed nations. This increased average paternal age has led to concerns about adverse effects of advanced paternal age on sperm quality, assisted reproductive outcomes, and the health of the offspring conceived by older fathers. This review discusses the association between advanced paternal age and sperm parameters, assisted reproduction success rates, and offspring health.
许多因素，包括推迟婚姻、预期寿命的延长和辅助生殖技术成功率的提高，都导致了发达国家父亲年龄的增长。这种平均父亲年龄的增长引起了人们对高龄父亲的精子质量、辅助生殖结果和由年龄较大的父亲所生育后代的健康产生不利影响的担忧。本文讨论了高龄父亲与精子参数、辅助生殖成功率和后代健康之间的关系。
