Mehrabani Sanaz, Asemi Mehdi, Najafian Jamshid, Sajjadi Firouzeh, Maghroun Maryam, Mohammadifard Noushin
Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2017 Aug 31;6:112. doi: 10.4103/2277-9175.213877. eCollection 2017.
There is evidence regarding the relationship between dietary proteins intake and blood pressure (BP), but they had inconsistent results. Therefore, this study was designed to assess the association between different kinds of protein intake (animal and plant protein) and BP.
Data were collected from Isfahan Healthy Heart Program. We performed a cross-sectional study among 9660 randomly selected Iranian adults aged ≥19-year-old that they were selected from three large Iranian regions in 2007. A simplified validated 48-item-food frequency questionnaire was used to assess dietary intake including all kinds of protein. Systolic and diastolic BPs were measured in duplicate by trained personnel using a standard protocol. Multivariable regressions were applied to assess the relationship between protein intake and BP levels and the presence of hypertension (HTN).
More frequent consumption of animal, plant, and total protein intake were inversely associated with BP in a crude model ( < 0.001); however, after adjustment for potential confounders this relationship remained only for plant protein ( = 0.04). The risk of HTN occurrence decreased in the highest quintile of total and plant protein consumption by 19% (odds ratio [OR] = 0.81; confidence interval [CI]: [0.65-0.96]; for trend = 0.004) and 18% (OR = 0.82; [CI: (0.67-0.94]; for trend = 0.03), respectively.
More frequent protein intake, especially plant protein consumption was inversely associated with BP and risk of HTN among Iranian adults.
有证据表明膳食蛋白质摄入量与血压（BP）之间存在关联，但结果并不一致。因此，本研究旨在评估不同种类蛋白质摄入量（动物蛋白和植物蛋白）与血压之间的关联。
数据来自伊斯法罕健康心脏项目。我们对9660名年龄≥19岁的伊朗成年人进行了一项横断面研究，这些人于2007年从伊朗三个大地区随机选取。使用一份经过简化验证的48项食物频率问卷来评估包括各类蛋白质在内的膳食摄入量。收缩压和舒张压由经过培训的人员按照标准方案重复测量。应用多变量回归来评估蛋白质摄入量与血压水平以及高血压（HTN）存在情况之间的关系。
在粗模型中，动物蛋白、植物蛋白和总蛋白摄入频率越高与血压呈负相关（<0.001）；然而，在对潜在混杂因素进行调整后，这种关系仅在植物蛋白方面仍然存在（=0.04）。在总蛋白和植物蛋白消费最高五分位数组中，高血压发生风险分别降低了19%（比值比[OR]=0.81；置信区间[CI]：[0.65 - 0.96]；趋势检验=0.004）和18%（OR = 0.82；[CI：(0.67 - 0.94]；趋势检验=0.03）。
在伊朗成年人中，更频繁的蛋白质摄入，尤其是植物蛋白消费与血压及高血压风险呈负相关。
