Coelho-Júnior Hélio José, Calvani Riccardo, Picca Anna, Tosato Matteo, Savera Giulia, Landi Francesco, Marzetti Emanuele
Department of Geriatrics and Orthopedics, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Fondazione Policlinico Universitario "A. Gemelli", IRCCS, 00168 Rome, Italy.
Metabolites. 2023 Mar 16;13(3):431. doi: 10.3390/metabo13030431.
The present study was conducted to test the association between protein intake and blood pressure, glucose levels, and blood cholesterol in a large sample of Italian older adults. Longevity Check-up 7+ (Lookup 7+) is an ongoing project that started in June 2015. The project is conducted in unconventional settings (e.g., exhibitions, malls, health promotion campaigns) across Italy with the aim of fostering adoption of healthy lifestyles in the general population. For the present study, participants were eligible if they were 65+ years and provided written informed consent. Systolic (SBP) and diastolic blood pressure (DBP), and blood glucose and cholesterol levels were assessed. Protein intake was estimated using a 12-item food frequency questionnaire. Three-thousand four-hundred and four older adults were included in the study. The results of the linear regression showed an inverse association between protein intake (as a continuous variable) and DBP, and a positive correlation with blood cholesterol levels. The findings of the present study indicate that a high intake of protein was negatively associated with DBP and positively associated with total blood cholesterol levels in a large cohort of Italian older adults, after adjustment for numerous covariates.
本研究旨在检验意大利大量老年人群中蛋白质摄入量与血压、血糖水平及血液胆固醇之间的关联。长寿体检7+（Lookup 7+）是一个始于2015年6月的正在进行的项目。该项目在意大利各地的非传统场所（如展览、商场、健康促进活动）开展，目的是促进普通人群采用健康的生活方式。在本研究中，年龄在65岁及以上并提供书面知情同意书的参与者符合条件。对收缩压（SBP）和舒张压（DBP）以及血糖和胆固醇水平进行了评估。使用一份包含12个条目的食物频率问卷来估计蛋白质摄入量。该研究纳入了3404名老年人。线性回归结果显示，蛋白质摄入量（作为连续变量）与DBP呈负相关，与血液胆固醇水平呈正相关。本研究结果表明，在对众多协变量进行调整后，在一大群意大利老年人中，高蛋白质摄入量与DBP呈负相关，与总血液胆固醇水平呈正相关。
