Kida Teruyo, Fukumoto Masanori, Sato Takaki, Oku Hidehiro, Ikeda Tsunehiko
Department of Ophthalmology, Osaka Medical College, Takatsuki, Japan.
Ophthalmologica. 2017;237(3):173-179. doi: 10.1159/000459636. Epub 2017 Mar 11.
The association of central retinal vein occlusion (CRVO) with primary open-angle glaucoma (POAG) or ocular hypertension has been reported, and lowering intraocular pressure (IOP) helps to improve the retinal circulation in eyes with CRVO. However, the clinical features of CRVOs with normal-tension glaucoma (NTG) are not well known. Therefore, we investigated Japanese CRVO patients with NTG.
We retrospectively investigated 234 CRVO patients over 5 years, with follow-ups of more than 12 months, and evaluated the prevalence of glaucoma.
Of the 234 CRVO patients, 18 (7.7%) were diagnosed with NTGs (n = 10) or POAGs (n = 8). Seven POAG (87.5%) and 3 NTG (30%) patients had systemic hypertension. At the initial CRVO evaluation, 6 NTGs showed a significantly increased IOP; mean IOP was 13.3 mm Hg before CRVO, 16.2 mm Hg at CRVO, and 13.5 mm Hg at the final visit.
The proportion of NTGs with systemic hypertension was low. IOP of NTG patients was significantly elevated at the initial CRVO evaluation, even in the presence of anti-glaucoma drugs.
视网膜中央静脉阻塞（CRVO）与原发性开角型青光眼（POAG）或高眼压症的关联已有报道，降低眼压（IOP）有助于改善CRVO患者的视网膜循环。然而，眼压正常性青光眼（NTG）合并CRVO的临床特征尚不清楚。因此，我们对日本NTG合并CRVO的患者进行了研究。
我们回顾性研究了234例CRVO患者，随访时间超过5年，随访时间超过12个月，并评估青光眼的患病率。
在234例CRVO患者中，18例（7.7%）被诊断为NTG（n = 10）或POAG（n = 8）。7例POAG（87.5%）和3例NTG（30%）患者患有系统性高血压。在初次CRVO评估时，6例NTG患者眼压显著升高；CRVO前平均眼压为13.3 mmHg，CRVO时为16.2 mmHg，最后一次随访时为13.5 mmHg。
NTG合并系统性高血压的比例较低。即使使用抗青光眼药物，NTG患者在初次CRVO评估时眼压仍显著升高。
