Moessinger A C, Fox H E, Higgins A, Rey H R, Haideri M A
Division of Perinatal Medicine, Columbia-Presbyterian Medical Center, New York.
Lancet. 1987 Dec 5;2(8571):1297-300. doi: 10.1016/s0140-6736(87)91193-7.
Fetal breathing activity was monitored by ultrasonography in 14 patients with oligohydramnios (4 with fetal anuria and 10 with premature rupture of the membranes). 45 patients with intact membranes, with normal amniotic fluid volume, and matched for gestational age were the controls. Fetal breathing movements were seen in all 8 patients who died in the perinatal period with a necropsy diagnosis of lung hypoplasia. While patients with premature rupture of the membranes (irrespective of outcome) spent the same or less time breathing than controls, fetuses with renal anomalies, oligohydramnios, and lung hypoplasia spent more time breathing than controls. The observation of fetal breathing activity is not helpful in identifying patients with oligohydramnios at risk of lung hypoplasia.
通过超声检查监测了14例羊水过少患者(4例胎儿无尿,10例胎膜早破)的胎儿呼吸活动。45例胎膜完整、羊水体积正常且孕周匹配的患者作为对照。在围产期死亡且尸检诊断为肺发育不全的所有8例患者中均观察到胎儿呼吸运动。虽然胎膜早破患者(无论结局如何)呼吸时间与对照组相同或更少,但有肾脏异常、羊水过少和肺发育不全的胎儿呼吸时间比对照组更长。观察胎儿呼吸活动无助于识别有肺发育不全风险的羊水过少患者。