Bioengineering Laboratory, RIKEN , 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
ACS Appl Mater Interfaces. 2017 Oct 4;9(39):34518-34525. doi: 10.1021/acsami.7b13841. Epub 2017 Sep 22.
A colorimetric method for fast, simple, and selective detection of Cu was developed using I-mediated etching of triangular gold nanoplates (AuNPLs). The method was based on our finding that Cu efficiently promoted this etching in the presence of SCN. The etching process was accompanied by a dramatic color change from blue to red, allowing for visual and spectroscopic detection of Cu with detection limits of 10 and 1 μM, respectively. When molecular recognition by a DNA aptamer was incorporated into this method, visual detection of chloramphenicol was also achieved with a detection limit of 5 μM.
一种使用 I 介导的三角金纳米板（AuNPLs）蚀刻快速、简单和选择性检测 Cu 的比色法被开发出来。该方法基于我们的发现，即在 SCN 的存在下，Cu 能有效地促进这种蚀刻。蚀刻过程伴随着从蓝色到红色的剧烈颜色变化，允许通过视觉和光谱检测 Cu，检测限分别为 10 和 1 μM。当将 DNA 适体的分子识别纳入该方法中时，氯霉素的可视化检测也实现了，检测限为 5 μM。
