Wilson Nick, Kvizhinadze Giorgi, Pega Frank, Nair Nisha, Blakely Tony
BODE3 Programme, Department of Public Health, University of Otago, Wellington, New Zealand.
PLoS One. 2017 Sep 14;12(9):e0184538. doi: 10.1371/journal.pone.0184538. eCollection 2017.
There is some evidence that home safety assessment and modification (HSAM) is effective in reducing falls in older people. But there are various knowledge gaps, including around cost-effectiveness and also the impacts at a health district-level.
A previously established Markov macro-simulation model built for the whole New Zealand (NZ) population (Pega et al 2016, Injury Prevention) was enhanced and adapted to a health district level. This district was Counties Manukau District Health Board, which hosts 42,000 people aged 65+ years. A health system perspective was taken and a discount rate of 3% was used for both health gain and costs. Intervention effectiveness estimates came from a systematic review, and NZ-specific intervention costs were extracted from a randomized controlled trial. In the 65+ age-group in this health district, the HSAM program was estimated to achieve health gains of 2800 quality-adjusted life-years (QALYs; 95% uncertainty interval [UI]: 547 to 5280). The net health system cost was estimated at NZ$8.44 million (95% UI: $663 to $14.3 million). The incremental cost-effectiveness ratio (ICER) was estimated at NZ$5480 suggesting HSAM is cost-effective (95%UI: cost saving to NZ$15,300 [equivalent to US$10,300]). Targeting HSAM only to people age 65+ or 75+ with previous injurious falls was estimated to be particularly cost-effective (ICERs: $700 and $832, respectively) with the latter intervention being cost-saving. There was no evidence for differential cost-effectiveness by sex or by ethnicity: Māori (Indigenous population) vs non-Māori.
This modeling study suggests that a HSAM program could produce considerable health gain and be cost-effective for older people at a health district level. Nevertheless, comparisons may be desirable with other falls prevention interventions such as group exercise programs, which also provide social contact and may prevent various chronic diseases.
有证据表明家庭安全评估与改善(HSAM)在减少老年人跌倒方面有效。但仍存在各种知识空白,包括成本效益以及在健康区层面的影响。
一个先前为新西兰全体人口建立的马尔可夫宏观模拟模型(Pega等人,2016年,《伤害预防》)得到改进,并适用于健康区层面。该健康区为曼努考县地区卫生委员会,有42000名65岁及以上的老年人。采用卫生系统视角,健康收益和成本均采用3%的贴现率。干预效果评估来自系统评价,新西兰特定的干预成本从一项随机对照试验中提取。在该健康区65岁及以上年龄组中,HSAM项目估计可实现2800个质量调整生命年(QALYs)的健康收益(95%不确定性区间[UI]:547至5280)。卫生系统净成本估计为844万新西兰元(95% UI:66.3万至1430万)。增量成本效益比(ICER)估计为5480新西兰元,表明HSAM具有成本效益(95% UI:节省成本至15300新西兰元[相当于10300美元])。仅针对65岁及以上或75岁及以上且有过跌倒致伤史的人群开展HSAM被估计特别具有成本效益(ICER分别为700美元和832美元),后一种干预措施节省成本。没有证据表明性别或种族(毛利人[原住民]与非毛利人)之间存在成本效益差异。
这项建模研究表明,HSAM项目可为健康区层面的老年人带来可观的健康收益且具有成本效益。然而,与其他预防跌倒干预措施(如集体锻炼项目,其还能提供社交接触并预防多种慢性病)进行比较可能是可取的。