Cramer H, Weigel K, Rissler K, Milos A, Wolf A, Mundinger F
Department of Neurology, University of Freiburg, FRG.
Neurol Res. 1987 Sep;9(3):205-10. doi: 10.1080/01616412.1987.11739797.
The concentration of somatostatin-like immunoreactivity (SLI) was determined by specific radioimmunoassay in the cerebroventricular fluid of patients with tumours of the basal midline and compared to findings in patients with multiple sclerosis. Mean SLI levels of the two groups were not significantly different. In patients with basal tumours (astrocytoma, craniopharyngioma, etc.) SLI levels varied widely and tended to increase with increased intracranial pressure. Lateral ventricular SLI levels decreased in patients with blockade of foramen Monro and in patients with communicating hydrocephalus or post-radiation encephalopathy. There was no apparent correlation with dysfunction of the hypothalamohypophyseal axis.
采用特异性放射免疫分析法测定了基底中线肿瘤患者脑脊液中生长抑素样免疫反应性（SLI）的浓度，并与多发性硬化症患者的结果进行了比较。两组的平均SLI水平无显著差异。在基底肿瘤（星形细胞瘤、颅咽管瘤等）患者中，SLI水平差异很大，且有随颅内压升高而升高的趋势。在Monro孔阻塞患者、交通性脑积水患者或放射后脑病患者中，侧脑室SLI水平降低。与下丘脑-垂体轴功能障碍无明显相关性。
