Lowry Lacy E, Zehring William A
Department of Basic Science, Geisinger Commonwealth School of Medicine, Scranton, PA, United States.
Department of Biochemistry, Geisinger Commonwealth School of Medicine, Scranton, PA, United States.
Front Immunol. 2017 Sep 1;8:1061. doi: 10.3389/fimmu.2017.01061. eCollection 2017.
It is widely acknowledged that the human immune system plays a crucial role in preventing the formation and progression of innumerable types of cancer (1). The mechanisms by which this occurs are numerous, including contributions from both the innate and adaptive immune systems. As such, immunotherapy has long been believed to be an auspicious solution in the treatment of malignancy (2). Recent research has highlighted the promise of natural killer (NK) cells as a more directed immunotherapy approach. This paper will focus on the methods of potentiation of NK cells for their use in cancer therapy.
人们普遍认为,人类免疫系统在预防无数类型癌症的形成和进展中起着关键作用(1)。发生这种情况的机制有很多,包括先天免疫系统和适应性免疫系统的作用。因此,长期以来,免疫疗法一直被认为是治疗恶性肿瘤的一种有前景的解决方案(2)。最近的研究突出了自然杀伤(NK)细胞作为一种更具针对性的免疫疗法的前景。本文将重点关注增强NK细胞用于癌症治疗的方法。