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在绝经后女性中,北欧式健走比传统步行训练更能增加循环血管内皮生长因子(VEGF)水平。

Nordic walking increases circulating VEGF more than traditional walking training in postmenopause.

作者信息

Izzicupo P, D'Amico M A, Di Blasio A, Napolitano G, Di Baldassarre A, Ghinassi B

机构信息

a Department of Medicine and Aging Science , University "G. d'Annunzio", Chieti-Pescara , Chieti , Pescara , Italy.

出版信息

Climacteric. 2017 Dec;20(6):533-539. doi: 10.1080/13697137.2017.1366979. Epub 2017 Sep 17.

DOI:10.1080/13697137.2017.1366979
PMID:28920458
Abstract

OBJECTIVES

Nordic walking (NW) is widely practiced by postmenopausal women. Its effects are peculiar owing to the involvement of more muscle groups than in traditional walking training (WT). Since mechanical load promotes secretion of vascular endothelial growth factor (VEGF) from both skeletal muscle and muscle endothelium, the aim of the study was to compare the effect of NW and WT on VEGF levels.

METHOD

Thirty postmenopausal women were randomly assigned to NW or WT. Both groups trained 40-50 min/day, three times per week, at a mean intensity of 12 on a 15-category scale of the ratings of perceived exertion. Since VEGF is also released from adipocytes, anthropometric parameters were assessed.

RESULTS

NW increased circulating VEGF more than WT (p = 0.041). Furthermore, both study groups exhibited an average decrease in weight (p = 0.023), body mass index (p = 0.024), hip circumference (p = 0.001), and arm fat index, although WT participants had higher values for this index at baseline (p < 0.001) and thus exhibited a greater net decrease compared with the NW participants (p < 0.011).

CONCLUSIONS

These data imply that NW increases the level of circulating VEGF more than does traditional walking when the intensity of training is equivalent.

摘要

目的

绝经后女性广泛进行北欧式健走(NW)。由于与传统步行训练(WT)相比,北欧式健走涉及更多肌肉群,其效果独特。鉴于机械负荷可促进骨骼肌和肌肉内皮细胞分泌血管内皮生长因子(VEGF),本研究旨在比较北欧式健走和传统步行训练对VEGF水平的影响。

方法

30名绝经后女性被随机分配至北欧式健走组或传统步行训练组。两组均每天训练40 - 50分钟,每周三次,自觉运动强度平均为15级量表中的12级。由于VEGF也由脂肪细胞释放,因此评估了人体测量参数。

结果

与传统步行训练相比,北欧式健走使循环VEGF水平升高更明显(p = 0.041)。此外,两个研究组的体重(p = 0.023)、体重指数(p = 0.024)、臀围(p = 0.001)和手臂脂肪指数均出现平均下降,尽管传统步行训练组参与者该指数的基线值更高(p < 0.001),因此与北欧式健走组参与者相比,其净下降幅度更大(p < 0.011)。

结论

这些数据表明,在训练强度相同的情况下相比于传统步行,北欧式健走能使循环VEGF水平升高得更多。

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