Pospieszna Barbara, Karolkiewicz Joanna, Tarnas Jacek, Lewandowski Jacek, Laurentowska Maria, Pilaczyńska-Szcześniak Łucja
Department of Physiology, Biochemistry and Hygiene, Poznań University of Physical Education, Poznań, Poland -
Department of Tourism and Recreation, Adam Mickiewicz University in Poznań, Poznań, Poland -
J Sports Med Phys Fitness. 2017 Sep;57(9):1178-1185. doi: 10.23736/S0022-4707.16.06528-2. Epub 2016 Sep 22.
The aim of this study was to evaluate the effects of a 12-week Nordic Walking (NW) intervention on nitric oxide synthase activity (eNOS), levels of antibodies against oxidatively modified low-density lipoproteins (oLAb), plasma antioxidant capacity (TAC), thiobarbituric acid reactive substance (TBARS) concentration, carbohydrate and lipid metabolism, and atherosclerosis risk factors (AIP) in postmenopausal women.
A sample of 39 women, divided into two comparable groups: training (N.=20) and control (N.=19), took part in the study. Participants in the training group performed a 12-week supervised NW training: 60-minute sessions of exercise, repeated three times per week. The biochemical and anthropometric data were obtained before and after the intervention. During the first and the last training sessions, the individual walking distance in trained group was measured.
After the intervention, significant differences in covered distance, body mass, BMI, fat mass, insulin level (P<0.01), systolic blood pressure and TBARS concentration (P<0.05) were found in trained women.
Applied training was able to improve functional capacity and body composition in healthy postmenopausal women. It appears to be no direct link between a significant decrease in the level of systolic blood pressure, the level of eNOS activity, TAC, oLAb and plasma TBARS concentration in trained women. It seems probable that NW training would be more effective for postmenopausal women with more severely impaired endothelial function.
本研究旨在评估为期12周的北欧健走（NW）干预对绝经后女性一氧化氮合酶活性（eNOS）、氧化修饰低密度脂蛋白抗体水平（oLAb）、血浆抗氧化能力（TAC）、硫代巴比妥酸反应物质（TBARS）浓度、碳水化合物和脂质代谢以及动脉粥样硬化风险因素（AIP）的影响。
39名女性样本被分为两个可比组：训练组（N = 20）和对照组（N = 19）参与研究。训练组参与者进行为期12周的有监督的NW训练：每次60分钟的锻炼，每周重复三次。在干预前后获取生化和人体测量数据。在第一次和最后一次训练期间，测量训练组的个体行走距离。
干预后，训练有素的女性在行走距离、体重、BMI、脂肪量、胰岛素水平（P<0.01）、收缩压和TBARS浓度（P<0.05）方面存在显著差异。
应用的训练能够改善健康绝经后女性的功能能力和身体成分。训练有素的女性收缩压水平、eNOS活性水平、TAC、oLAb和血浆TBARS浓度的显著降低之间似乎没有直接联系。对于内皮功能受损更严重的绝经后女性，NW训练可能更有效。
