大麻与精神分裂症。一项对瑞典应征入伍者的纵向研究。
Cannabis and schizophrenia. A longitudinal study of Swedish conscripts.
作者信息
Andréasson S, Allebeck P, Engström A, Rydberg U
机构信息
Karolinska Institutet, Department of Social Medicine, Huddinge, Sweden.
出版信息
Lancet. 1987 Dec 26;2(8574):1483-6. doi: 10.1016/s0140-6736(87)92620-1.
The association between level of cannabis consumption and development of schizophrenia during a 15-year follow-up was studied in a cohort of 45,570 Swedish conscripts. The relative risk for schizophrenia among high consumers of cannabis (use on more than fifty occasions) was 6.0 (95% confidence interval 4.0-8.9) compared with non-users. Persistence of the association after allowance for other psychiatric illness and social background indicated that cannabis is an independent risk factor for schizophrenia.
在一个由45570名瑞典应征入伍者组成的队列中，研究了15年随访期间大麻消费水平与精神分裂症发病之间的关联。与不使用者相比，大麻高消费者（使用超过50次）患精神分裂症的相对风险为6.0（95%置信区间4.0 - 8.9）。在考虑其他精神疾病和社会背景后，这种关联仍然存在，这表明大麻是精神分裂症的一个独立风险因素。
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