Andréasson S, Allebeck P
Department of Medicine, Karolinska Institute, Huddinge University Hospital, Sweden.
Scand J Soc Med. 1990;18(1):9-15. doi: 10.1177/140349489001800102.
The association between level of cannabis consumption and mortality during a 15-year follow-up was studied in a cohort of 45,540 Swedish conscripts. The relative risk of death among high consumers of cannabis (use on more than 50 occasions) was 2.8 (95% confidence interval (1.9-4.1)) compared with non-users. However, after control for social background variables in a multivariate model, no excess mortality was found. A high level of consumption of other drugs was also associated with increased mortality; the relative risk of high consumption (greater than 50 times) was 4.6 (2.4-8.5) compared with non-users. After adjustment for social background a relative risk of 1.2 (0.8-1.9) remained; for those having used drugs intravenously more than once, the relative risk was 1.6 (0.9-2.7). Among causes of death a strong predominance was found for violent death, suicide or uncertain suicide being the single most important accounting for 34.4% of all deaths. The proportion of suicides increased sharply with the level of cannabis consumption.
在一个由45540名瑞典应征入伍者组成的队列中,研究了15年随访期间大麻消费水平与死亡率之间的关联。与不使用者相比,大麻高消费者(使用超过50次)的相对死亡风险为2.8(95%置信区间(1.9 - 4.1))。然而,在多变量模型中对社会背景变量进行控制后,未发现额外的死亡率。其他药物的高消费水平也与死亡率增加有关;与不使用者相比,高消费(超过50次)的相对风险为4.6(2.4 - 8.5)。在对社会背景进行调整后,相对风险仍为1.2(0.8 - 1.9);对于那些静脉注射毒品超过一次的人,相对风险为1.6(0.9 - 2.7)。在死亡原因中,暴力死亡占主导地位,自杀或不明自杀是所有死亡中最重要的单一原因,占所有死亡的34.4%。自杀比例随着大麻消费水平的升高而急剧增加。