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青蛙味觉神经对酸刺激反应的阳离子依赖性

Cation dependence of frog gustatory neural responses to acid stimuli.

作者信息

Okada Y, Miyamoto T, Sato T

机构信息

Department of Physiology, Nagasaki University School of Dentistry, Japan.

出版信息

Comp Biochem Physiol A Comp Physiol. 1987;88(3):487-90. doi: 10.1016/0300-9629(87)90068-5.

Abstract
  1. To understand the mechanism underlying the gustatory response for acid stimuli, the characteristics of glossopharyngeal neural responses elicited by 1 mM hydrochloric acid (HCl) in bullfrogs were examined by changing the ionic composition of adapting solutions flowed on the tongue surface. 2. The amplitude of the gustatory neural response for HCl was increased with an increase of Ca2+ concentration in the adapting solution. 3. The action of Ca2+ in the adapting solution could be replaced by Ba2+ and Sr2+, and was inhibited by Co2+, suggesting that the Ca2+ channel in the receptor membrane of taste cells is related to a gustatory neural response to acid.
摘要
  1. 为了解酸刺激味觉反应的潜在机制,通过改变流在舌表面的适应溶液的离子组成,研究了1 mM盐酸(HCl)引起的牛蛙舌咽神经反应的特征。2. HCl味觉神经反应的幅度随着适应溶液中Ca2+浓度的增加而增大。3. 适应溶液中Ca2+的作用可被Ba2+和Sr2+替代,并受到Co2+的抑制,这表明味觉细胞受体膜中的Ca2+通道与对酸的味觉神经反应有关。

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