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参考标准以及妊娠山羊(Capra hircus)作为产科研究中人类模型的生理学意义。

Reference standards and the physiologic significance of the pregnant goat (Capra hircus) as a human model in obstetrical research.

作者信息

Cissik J H, Hankins G D, Snyder R R, Ehler W J, Pierson W A

机构信息

Wilford Hall USAF Medical Center, Lackland AFB, TX 78236.

出版信息

Comp Biochem Physiol A Comp Physiol. 1987;88(3):533-7. doi: 10.1016/0300-9629(87)90076-4.

DOI:10.1016/0300-9629(87)90076-4
PMID:2892628
Abstract
  1. Amniotic fluid, cerebrospinal fluid, serum, and urine chemistries; respiratory rate and arterial and mixed venous blood gases; heart rate, hematocrit, and cardiac output; and arterial, pulmonary artery, central venous and pulmonary wedge pressures were measured in 20 pregnant adult goats of 19.5-34 kg body weight. 2. Arithmetic means, standard deviations, and coefficients of variation were calculated to develop reference values; in addition, the 95% confidence limits for ranges were established. 3. Comparison of derived data with that from non-pregnant goats shows changes similar to those seen when examining pregnant and non-pregnant humans. 4. These results indicate the pregnant goat is an acceptable model for human obstetrical research.
摘要
  1. 对20只体重在19.5 - 34千克的成年妊娠山羊测量羊水、脑脊液、血清和尿液化学指标;呼吸频率以及动脉血和混合静脉血气;心率、血细胞比容和心输出量;以及动脉压、肺动脉压、中心静脉压和肺楔压。2. 计算算术平均值、标准差和变异系数以制定参考值;此外,还确定了范围的95%置信限。3. 将所得数据与非妊娠山羊的数据进行比较,结果显示出与检查妊娠和非妊娠人类时相似的变化。4. 这些结果表明,妊娠山羊是人类产科研究的一个可接受的模型。

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