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Risk factors and outcomes of fetal macrosomia in a tertiary centre in Tanzania: a case-control study.坦桑尼亚一家三级医疗中心巨大胎儿的危险因素与结局：一项病例对照研究。
BMC Pregnancy Childbirth. 2016 Aug 24;16(1):243. doi: 10.1186/s12884-016-1044-3.
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The prevalence of hyperglycaemia in pregnancy in Australia.澳大利亚妊娠期高血糖的患病率。
Aust N Z J Obstet Gynaecol. 2016 Aug;56(4):341-5. doi: 10.1111/ajo.12447. Epub 2016 Feb 23.
3
Searching for the definition of macrosomia through an outcome-based approach in low- and middle-income countries: a secondary analysis of the WHO Global Survey in Africa, Asia and Latin America.通过基于结果的方法在低收入和中等收入国家探寻巨大儿的定义：对世界卫生组织在非洲、亚洲和拉丁美洲进行的全球调查的二次分析
BMC Pregnancy Childbirth. 2015 Dec 3;15:324. doi: 10.1186/s12884-015-0765-z.
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Induction of labour versus expectant management for large-for-date fetuses: a randomised controlled trial.大胎儿引产与期待管理的随机对照试验。
Lancet. 2015 Jun 27;385(9987):2600-5. doi: 10.1016/S0140-6736(14)61904-8. Epub 2015 Apr 8.
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Is gestational diabetes mellitus an independent risk factor for macrosomia: a meta-analysis?妊娠期糖尿病是巨大儿的独立危险因素吗：一项荟萃分析？
Arch Gynecol Obstet. 2015 Apr;291(4):729-35. doi: 10.1007/s00404-014-3545-5. Epub 2014 Nov 12.
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Searching for the definition of macrosomia through an outcome-based approach.通过基于结果的方法寻找巨大儿的定义。
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Diagnostic criteria and classification of hyperglycaemia first detected in pregnancy: a World Health Organization Guideline.妊娠期间首次检测出血糖异常的诊断标准与分类：世界卫生组织指南
Diabetes Res Clin Pract. 2014 Mar;103(3):341-63. doi: 10.1016/j.diabres.2013.10.012.
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Testing for gestational diabetes mellitus in Australia.澳大利亚的妊娠期糖尿病检测。
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Australian national birthweight percentiles by sex and gestational age, 1998-2007.澳大利亚 1998-2007 年按性别和胎龄划分的全国出生体重百分位数。
Med J Aust. 2012 Sep 3;197(5):291-4. doi: 10.5694/mja11.11331.
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Maternal and neonatal outcomes of large for gestational age pregnancies.巨大儿妊娠的母婴结局。
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饮食控制的妊娠期糖尿病女性的巨大儿发生率：一项回顾性研究

Macrosomia Rates in Women with Diet-Controlled Gestational Diabetes: A Retrospective Study.

作者信息

Vally Fatima, Presneill Jeffrey, Cade Thomas

机构信息

Department of Maternal Fetal Medicine, Pregnancy Research Centre, Royal Women's Hospital, 20 Flemington Road, Parkville, Melbourne, VIC, Australia.

The Royal Melbourne Hospital, City Campus, 300 Grattan St, Melbourne, VIC, Australia.

出版信息

J Pregnancy. 2017;2017:4935397. doi: 10.1155/2017/4935397. Epub 2017 Aug 27.

DOI:10.1155/2017/4935397
PMID:28928985
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5591990/
Abstract

BACKGROUND

Current data on the rates of macrosomia in women with gestational diabetes mellitus (GDM) are heterogenous. No study has specifically examined macrosomia rates in women with diet-controlled gestational diabetes.

AIMS

To compare the rates of macrosomia between mothers with diet-controlled GDM to mothers without diabetes mellitus.

METHODS

A retrospective study in which all patients with diet-controlled GDM and singleton pregnancies in 2014 were considered for inclusion in the study. These cases were individually matched to mothers without GDM and without type 1 or 2 diabetes. Cases were matched to parity, age, and BMI. Controls were selected from the same year and as close as possible to the date of delivery of the case. Primary outcomes were macrosomia, defined by estimated fetal weight >90th centile and >95th centile (separately).

RESULTS

The estimated adjusted odds ratio for the presence of maternal GDM in the presence of EFW > 90th percentile (adjusted for maternal age, BMI, gravidity, parity, baby gender, and EGA) was 0.63 (95% CI 0.30-1.3; = 0.21). The estimated adjusted odds ratio for the association of maternal GDM and EFW > 95th percentile was 0.66 (95% CI 0.26-1.7; = 0.38).

CONCLUSIONS

Our findings suggest that macrosomia is not increased in women with diet-controlled GDM. The study registration number is AQA 16/01.

摘要

背景

目前关于妊娠期糖尿病（GDM）女性巨大儿发生率的数据存在异质性。尚无研究专门调查饮食控制的妊娠期糖尿病女性的巨大儿发生率。

目的

比较饮食控制的GDM母亲与非糖尿病母亲的巨大儿发生率。

方法

一项回顾性研究，纳入2014年所有饮食控制的GDM单胎妊娠患者。这些病例与无GDM且无1型或2型糖尿病的母亲进行个体匹配。病例按产次、年龄和体重指数进行匹配。对照选自同一年，且尽可能接近病例的分娩日期。主要结局为巨大儿，分别定义为估计胎儿体重>第90百分位数和>第95百分位数。

结果

在估计胎儿体重>第90百分位数时（根据母亲年龄、体重指数、孕次、产次、胎儿性别和孕周调整），母亲患GDM的估计调整比值比为0.63（95%可信区间0.30 - 1.3；P = 0.21）。母亲患GDM与估计胎儿体重>第95百分位数之间关联的估计调整比值比为0.66（95%可信区间0.26 - 1.7；P = 0.38）。

结论

我们的研究结果表明，饮食控制的GDM女性中巨大儿发生率并未增加。研究注册号为AQA 16/01。