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在自由活动的幼年斑马鱼中快速进行全脑神经活动成像()。

Rapid whole brain imaging of neural activity in freely behaving larval zebrafish ().

机构信息

Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

Center for Integrative Imaging, Hefei National Laboratory for Physical Sciences at Microscale, CAS Center for Excellence in Brain Science and Intelligence Technology, School of Life Sciences, University of Science and Technology of China, Hefei, China.

出版信息

Elife. 2017 Sep 20;6:e28158. doi: 10.7554/eLife.28158.

Abstract

The internal brain dynamics that link sensation and action are arguably better studied during natural animal behaviors. Here, we report on a novel volume imaging and 3D tracking technique that monitors whole brain neural activity in freely swimming larval zebrafish (). We demonstrated the capability of our system through functional imaging of neural activity during visually evoked and prey capture behaviors in larval zebrafish.

摘要

内部大脑动态将感觉和行动联系起来,可以说在自然动物行为期间得到了更好的研究。在这里,我们报告了一种新颖的体积成像和 3D 跟踪技术,可监测自由游动的幼虫斑马鱼()的整个大脑神经活动。我们通过在幼虫斑马鱼的视觉诱发和猎物捕获行为期间对神经活动进行功能成像,展示了我们系统的能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7bc/5644961/c0015b239400/elife-28158-fig1.jpg

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