Ahrens Misha B, Engert Florian
Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
Harvard University, Department of Molecular and Cellular Biology, Cambridge, MA, USA.
Curr Opin Neurobiol. 2015 Jun;32:78-86. doi: 10.1016/j.conb.2015.01.007. Epub 2015 Jan 28.
The dense connectivity in the brain means that one neuron's activity can influence many others. To observe this interconnected system comprehensively, an aspiration within neuroscience is to record from as many neurons as possible at the same time. There are two useful routes toward this goal: one is to expand the spatial extent of functional imaging techniques, and the second is to use animals with small brains. Here we review recent progress toward imaging many neurons and complete populations of identified neurons in small vertebrates and invertebrates.
大脑中密集的连接意味着一个神经元的活动可以影响许多其他神经元。为了全面观察这个相互连接的系统，神经科学领域的一个愿望是同时记录尽可能多的神经元。实现这一目标有两条有效途径：一是扩大功能成像技术的空间范围，二是使用脑容量小的动物。在这里，我们回顾了在对小型脊椎动物和无脊椎动物中的许多神经元以及已识别神经元的完整群体进行成像方面的最新进展。
