伊朗北部巴博勒地区胃癌患者术后生存率及其影响因素的评估：2006 - 2011年

Estimating postoperative survival rate of gastric cancer patients and its effective factors in Babol, northern Iran: 2006-2011.

作者信息

Modarres Seyed-Reza, Gholizadeh-Pasha Abdolrahim, Khatibi Soheil, Siadati Sepideh

机构信息

Department of Surgery, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran.

Babol University of Medical Sciences, Babol, Iran.

出版信息

Caspian J Intern Med. 2017 Summer;8(3):190-195. doi: 10.22088/cjim.8.3.190.

DOI:10.22088/cjim.8.3.190

PMID:28932371

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5596190/

Abstract

BACKGROUND

The importance of gastric cancer, considering its progressive course and high mortality is one of the reasons we pay attention to patients' survival and the significance of this study was to estimate survival and determine the effective factors on patients with gastric cancer.

METHODS

In this cross-sectional study, all patients with gastric cancer who underwent surgery in Shahid Beheshti Hospital, Babol, northern Iran during 2006-2011 were enrolled. To get information, a checklist was prepared consisting gender, age, and other factors related to survival from the start of diagnosis to the end of study. Statistical analysis was performed using SPSS Version 20, t-test, chi-square test and Cox regression and Kaplan-Meier.

RESULTS

One hundred seventy-five patients consisting 132(75.4%) males and 43(24.6%) females entered the study. Among the 146 patients who were followed up for 50 months, 25 (14.28%) cases survived and 121 (69.15%) cases died. Survival did not have a significant association with gender, age, family history, smoking, location and type of tumor, metastasis, involved lymph nodes and treatment. Tumor stage and type of surgery had a significant association with survival in Cox regression.

CONCLUSION

Diagnosis of cancer at the early stage and type of surgery increased survival rate.

摘要

背景

考虑到胃癌病程进展及高死亡率，其重要性是我们关注患者生存情况的原因之一。本研究的意义在于评估胃癌患者的生存率，并确定影响其生存的相关因素。

方法

在这项横断面研究中，纳入了2006年至2011年期间在伊朗北部巴博勒市沙希德·贝赫什提医院接受手术的所有胃癌患者。通过一份包含性别、年龄以及从诊断开始到研究结束期间与生存相关的其他因素的清单来获取信息。使用SPSS 20版软件进行统计分析，采用t检验、卡方检验、Cox回归分析以及Kaplan-Meier分析。

结果

175例患者进入研究，其中男性132例（75.4%），女性43例（24.6%）。在146例接受了50个月随访的患者中，25例（14.28%）存活，121例（69.15%）死亡。生存情况与性别、年龄、家族史、吸烟、肿瘤位置和类型、转移情况、受累淋巴结及治疗方式均无显著关联。在Cox回归分析中，肿瘤分期和手术类型与生存情况存在显著关联。