Mwita Julius Chacha, Magafu Mgaywa Gilbert Mjungu Damas, Omech Bernard, Tsima Billy, Dewhurst Matthew J, Goepamang Monkgogi, Mashalla Yohana
Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Department of Cardiology, University Hospital Hartlepool, Hartlepool, UK.
SAGE Open Med. 2017 Sep 12;5:2050312117731473. doi: 10.1177/2050312117731473. eCollection 2017.
The objective of this study was to determine the burden of diagnosed and undiagnosed type 2 diabetes mellitus among patients hospitalised with acute heart failure in Botswana.
The study enrolled 193 consecutive patients admitted with acute heart failure to the medical wards at Princess Marina Hospital in Gaborone. Patients were classified as previously known diabetics, undiagnosed diabetics (glycated haemoglobin ≥ 6.5%) or as non-diabetics (glycated haemoglobin < 6.5%). Data on other comorbid conditions such as hypertension, atrial fibrillation, ischaemic heart disease, stroke, and renal failure were also collected.
The mean (SD) age of the participants was 54.2 (17.1) years and 53.9% were men. The percentage of known and undiagnosed diabetes mellitus was 15.5% and 12.4%, respectively. Diabetic patients were significantly more likely to have hypertension (77.8% vs 46.0%, p < 0.001), ischaemic heart disease (20.4% vs 5.0%, p < 0.001), chronic kidney disease (51.3% vs 23.0%, p < 0.001), and stroke (20.4% vs 5.8%, p < 0.01). In addition, diabetics were older than non-diabetics (61.0 years vs 51.6 years, p < 0.001).
About 27.9% of patients admitted with acute heart failure in Botswana had diabetes, and almost half of them presented with undiagnosed diabetes. These findings indicate that all hospitalised patients should be screened for diabetes.
本研究的目的是确定博茨瓦纳因急性心力衰竭住院患者中已诊断和未诊断的2型糖尿病负担。
该研究纳入了193例连续入住哈博罗内公主玛丽娜医院内科病房的急性心力衰竭患者。患者被分类为既往已知糖尿病患者、未诊断糖尿病患者（糖化血红蛋白≥6.5%）或非糖尿病患者（糖化血红蛋白<6.5%）。还收集了其他合并症的数据，如高血压、心房颤动、缺血性心脏病、中风和肾衰竭。
参与者的平均（标准差）年龄为54.2（17.1）岁，53.9%为男性。已知和未诊断糖尿病的百分比分别为15.5%和12.4%。糖尿病患者患高血压（77.8%对46.0%，p<0.001）、缺血性心脏病（20.4%对5.0%，p<0.001）、慢性肾病（51.3%对23.0%，p<0.001）和中风（20.4%对5.8%，p<0.01）的可能性显著更高。此外，糖尿病患者比非糖尿病患者年龄更大（61.0岁对51.6岁，p<0.001）。
在博茨瓦纳，约27.9%因急性心力衰竭住院的患者患有糖尿病，其中近一半为未诊断糖尿病。这些发现表明，所有住院患者都应进行糖尿病筛查。
