Yanagisawa Osamu, Sanomura Manabu
Faculty of Business and Information Sciences, Jobu University, Isesaki, Gunma, Japan.
Faculty of Medical Technology, Teikyo University, Itabashi, Tokyo, Japan.
Interv Med Appl Sci. 2017 Jun;9(2):67-75. doi: 10.1556/1646.9.2017.2.16.
We aimed to evaluate the effects of low-load resistance exercise with blood flow restriction (BFR) on high-energy phosphate metabolism, intracellular pH, and oxygenation level in the skeletal muscle. Seven males performed low-load ankle plantar flexion exercise (120 repetitions, 30% of one-repetition maximum) with and without BFR (130% of systolic blood pressure) inside a magnetic resonance device. Inorganic phosphate (Pi)-to-phosphocreatine (PCr) ratio, intracellular pH, and tissue oxygenation index (TOI) in the medial gastrocnemius were determined using P-magnetic resonance spectroscopy and near-infrared spectroscopy before and during exercise. The Pi-to-PCr ratio significantly increased during exercise in both conditions, with the BFR-condition values significantly exceeding the control-condition values. The BFR and control conditions showed significantly decreased intracellular pH during exercise, with the BFR-condition values being significantly lower than the control-condition values. The TOI significantly decreased during both exercises, but the decreases in the BFR condition were significantly greater than those observed in the control condition. Low-load BFR exercise places greater metabolic stress (greater PCr depletion, lower intracellular pH, and lower oxygenation level) on an exercising muscle than low-load non-restricted exercise.
我们旨在评估低负荷血流限制（BFR）抗阻运动对骨骼肌高能磷酸代谢、细胞内pH值和氧合水平的影响。七名男性在磁共振设备内进行了有或无BFR（收缩压的130%）的低负荷踝关节跖屈运动（120次重复，一次重复最大值的30%）。在运动前和运动期间，使用磷磁共振波谱和近红外光谱法测定腓肠肌内侧的无机磷酸盐（Pi）与磷酸肌酸（PCr）的比值、细胞内pH值和组织氧合指数（TOI）。在两种情况下，运动期间Pi与PCr的比值均显著增加，BFR组的值显著超过对照组的值。BFR组和对照组在运动期间细胞内pH值均显著降低，BFR组的值显著低于对照组的值。两种运动期间TOI均显著降低，但BFR组的降低幅度显著大于对照组。与低负荷无限制运动相比，低负荷BFR运动对运动肌肉造成更大的代谢压力（更大的PCr消耗、更低的细胞内pH值和更低的氧合水平）。
