Alenazi Aqeel M, Alshehri Mohammed M, Hoover Jeffrey C, Yabroudi Mohammad A, Kachanathu Shaji John, Liu Wen
1 Department of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center , Kansas City, KS.
2 Department of Rehabilitation Health Sciences and Physical Therapy, Prince Sattam Bin Abdulaziz University , Alkharj, Kingdom of Saudi Arabia .
J Altern Complement Med. 2018 Mar;24(3):220-230. doi: 10.1089/acm.2017.0104. Epub 2017 Sep 21.
Cardiovascular disease is a common health problem resulting from many factors, including dyslipidemia. T'ai chi is one of the interventions assigned to improve lipid profiles and other physical outcomes. However, conflicting results might be attributed to different study designs and interventional approaches. A systematic review and meta-analysis are needed to evaluate existing evidence.
The aim of this systematic review and meta-analysis is to evaluate existing randomized clinical trials (RCTs) regarding the overall effect of t'ai chi exercise on lipid profiles.
Electronic databases (MEDLINE and Cumulative Index to Nursing and Allied Health Literature) were searched. The authors included only English peer reviewed published RCTs that used a t'ai chi intervention and high-density lipoprotein cholesterol (HDL-C) as the primary outcome along with low-density lipoprotein cholesterol (LDL-C) and/or total cholesterol (TC) as secondary outcomes.
The authors identified 37 potentially eligible studies. Only eight RCTs were eligible for their qualitative review, and seven studies were eligible for meta-analysis. The included studies were rated as having a low risk of bias. Despite the overall low risk of bias, all studies failed to blind participants to group assignment and were generally unclear about whether they were selectively reporting data. A fixed effect model (I = 38.16%) demonstrated a small positive effect of t'ai chi on HDL-C (Cohen d = 0.12; standard error [SE] = 0.067; p = 0.037). A random effect model demonstrated a medium effect and small effect for LDL-C (Cohen d = 0.47; SE = 0.347; p = 0.089) and TC (Cohen d = 0.34; SE = 0.225; p = 0.066), respectively.
T'ai chi may potentially be beneficial on lipid profiles across different age groups and populations. Although there were conflicting results regarding the effect of t'ai chi on lipid profiles, the majority of studies had at least a small positive effect indicating a potential positive effect of t'ai chi on HDL-C, LDL-C, and/or TC. Therefore, further research is needed to confirm the small positive effect of t'ai chi on lipid profiles found in this review.
心血管疾病是一个常见的健康问题，由多种因素导致，包括血脂异常。太极拳是被指定用于改善血脂水平和其他身体指标的干预措施之一。然而，相互矛盾的结果可能归因于不同的研究设计和干预方法。需要进行系统评价和荟萃分析来评估现有证据。
本系统评价和荟萃分析的目的是评估现有关于太极拳运动对血脂水平总体影响的随机临床试验（RCT）。
检索电子数据库（MEDLINE和护理及相关健康文献累积索引）。作者仅纳入了以太极拳干预和高密度脂蛋白胆固醇（HDL-C）作为主要结局，以及低密度脂蛋白胆固醇（LDL-C）和/或总胆固醇（TC）作为次要结局的英文同行评审发表的RCT。
作者识别出37项潜在符合条件的研究。仅有8项RCT符合定性评价的条件，7项研究符合荟萃分析的条件。纳入的研究被评为偏倚风险较低。尽管总体偏倚风险较低，但所有研究均未对参与者进行分组隐匿，并且普遍不清楚它们是否选择性报告数据。固定效应模型（I² = 38.16%）显示太极拳对HDL-C有小的正向效应（科恩d = 0.12；标准误[SE] = 0.067；p = 0.037）。随机效应模型分别显示太极拳对LDL-C（科恩d = 0.47；SE = 0.347；p = 0.089）和TC（科恩d = 0.34；SE = 0.225；p = 0.066）有中等效应和小的效应。
太极拳可能对不同年龄组和人群的血脂水平有益。尽管关于太极拳对血脂水平的影响存在相互矛盾的结果，但大多数研究至少有小的正向效应，表明太极拳对HDL-C、LDL-C和/或TC有潜在正向效应。因此，需要进一步研究来证实本评价中发现的太极拳对血脂水平的小的正向效应。
