Frakulli Rezarta, Cammelli Silvia, Salvi Fabrizio, Balestrini Damiano, Baldissera Antonella, Degli Esposti Claudio, Martelli Ombretta, Abate Massimo, Piaoli Anna, Ferrari Stefano, Morganti Alessio G, Frezza Giovanni Piero
Radiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine - DIMES, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy.
Radiation Oncology Unit, Bellaria Hospital, Bologna, Italy.
Ann Transl Med. 2017 Sep;5(17):344. doi: 10.21037/atm.2017.05.25.
Cardiac metastases from sarcoma are uncommon. Due to their rarity there is not a standard of care. However, complete cardiac metastases resection is the best option but most of patients has widespread disease. In these patients palliative radiotherapy (RT) might improve symptoms and prevent further cardiac function decline. Here we present the case of a symptomatic 30-year-old woman with spindle cell sarcoma metastasis of right ventriculum and widespread disease. The patient received radiotherapy to the heart with palliative intent. Cardiac metastases represent a challenging clinic problem. Treatment should be individualized in a multidisciplinary setting, when possible surgery seems to be the best options. However, radiotherapy even in case of widespread disease can improve clinical control symptoms by reducing the mass effect.
肉瘤的心脏转移并不常见。由于其罕见性,目前尚无标准的治疗方案。然而,完整切除心脏转移灶是最佳选择,但大多数患者存在广泛转移。对于这些患者,姑息性放疗(RT)可能改善症状并防止心脏功能进一步下降。在此,我们报告一例有症状的30岁女性,患有右心室梭形细胞肉瘤转移且存在广泛转移。该患者接受了以姑息为目的的心脏放疗。心脏转移是一个具有挑战性的临床问题。治疗应在多学科环境中个体化,若可能,手术似乎是最佳选择。然而,即使在广泛转移的情况下,放疗也可通过减轻肿块效应改善临床症状控制。