Downie Laura E, Craig Jennifer P
Department of Optometry and Vision Sciences, The University of Melbourne, Melbourne, Victoria, Australia.
Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, Auckland, New Zealand.
Clin Exp Optom. 2017 Sep;100(5):438-458. doi: 10.1111/cxo.12597.
The human tear film is a highly ordered structure consisting of a thin layer of lipid on the surface and a thicker aqueous-mucin phase, which increases in mucin concentration toward the corneal epithelial cell layer. The health of the tear film and ocular surface influences the likelihood of being able to achieve successful contact lens wear. Contact lens discomfort and dryness are the most frequent reasons why contact lens wearers experience reduced wearing times, which can eventually lead to contact lens discontinuation. Comprehensive clinical assessment of tear film integrity and ocular surface health is therefore essential prior to commencing contact lens wear, to enable the ocular surface environment to be optimised to support lens wear. These parameters should also be evaluated over the course of contact lens wear, in order to identify any aspects requiring clinical management and ensure maintenance of optimal lens-wearing conditions. This review summarises current knowledge relating to the effects of soft contact lens wear on the tear film and ocular surface. It also provides a systematic approach to evaluating tear film and ocular surface integrity, in order to guide the clinical management of tear film anomalies with respect to contact lens wear.
人泪膜是一种高度有序的结构,其表面有一层薄薄的脂质,还有一层较厚的水 - 黏液相,黏液浓度朝着角膜上皮细胞层增加。泪膜和眼表的健康状况会影响成功佩戴隐形眼镜的可能性。隐形眼镜不适和干涩是隐形眼镜佩戴者减少佩戴时间的最常见原因,这最终可能导致停止佩戴隐形眼镜。因此,在开始佩戴隐形眼镜之前,对泪膜完整性和眼表健康进行全面的临床评估至关重要,以便优化眼表环境以支持镜片佩戴。在隐形眼镜佩戴过程中也应评估这些参数,以便识别任何需要临床处理的方面,并确保维持最佳的镜片佩戴条件。本综述总结了有关软性隐形眼镜佩戴对泪膜和眼表影响的当前知识。它还提供了一种评估泪膜和眼表完整性的系统方法,以指导针对隐形眼镜佩戴的泪膜异常的临床处理。