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特应性皮炎患者 14 岁以上对真菌的致敏情况及其与食物过敏反应发生的关系。

Sensitisation to fungi in atopic dermatitis patients over 14 years of age and the relation to the occurrence of food hypersensitivity reactions.

机构信息

Department of Dermatology and Venereology, Faculty Hospital and Medical Faculty of Charles University, Hradec Králové, Czech Republic.

Department of Medical Biophysics, Medical Faculty of Charles University, Hradec Králové, Czech Republic.

出版信息

Mycoses. 2018 Feb;61(2):88-95. doi: 10.1111/myc.12707. Epub 2017 Oct 10.

Abstract

The aim of this study was to evaluate if there is some relation between the sensitisation to fungi and the occurrence of food hypersensitivity reactions in atopic dermatitis patients aged 14 years and older. Complete dermatological and allergological examination was performed in all included patients; the occurrence of food hypersensitivity reactions was recorded and the sensitisation to mixture of fungi was examined (skin prick test, specific IgE). The statistical evaluation of the relation between the sensitisation to fungi and the occurrence of food hypersensitivity reactions was performed; 331 patients were included in the study, 110 men and 221 women, the average age was 26.8 years. The sensitisation to fungi was recorded in 100 patients (30%), the occurrence of food hypersensitivity reactions was recorded in 261 patients (79%). We confirmed that patients suffering from sensitisation to fungi suffer significantly more often from food hypersensitivity reactions to nuts (walnuts, peanuts) and sea fish; no significant relation was confirmed between the sensitisation to fungi and the occurrence of food hypersensitivity reactions to tomatoes, kiwi, apples, spices, oranges, capsicum, celery and carrot.

摘要

本研究旨在评估在 14 岁及以上特应性皮炎患者中,对真菌的致敏与食物过敏反应的发生是否存在某种关系。所有纳入的患者均进行了完整的皮肤科和过敏科检查;记录食物过敏反应的发生情况,并检查对真菌混合物的致敏情况(皮肤点刺试验、特异性 IgE)。对真菌致敏与食物过敏反应发生之间的关系进行了统计学评估;研究共纳入 331 例患者,其中男性 110 例,女性 221 例,平均年龄为 26.8 岁。记录了 100 例(30%)患者对真菌的致敏,261 例(79%)患者发生食物过敏反应。我们证实,对真菌致敏的患者更常发生对坚果(核桃、花生)和海鱼的食物过敏反应;对真菌致敏与对番茄、奇异果、苹果、香料、橙子、辣椒、芹菜和胡萝卜的食物过敏反应之间未确认到显著关系。

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