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14岁以上特应性皮炎患者对海鱼的食物过敏反应——与其他过敏性疾病及参数的相关性评估

Food Hypersensitivity Reactions to Seafish in Atopic Dermatitis Patients Older than 14 Year of Age - The Evaluation of Association with Other Allergic Diseases and Parameters.

作者信息

Čelakovská Jarmila, Josef Bukač, Vaneckova Jaroslava, Krcmova Irena, Komorousová Michaela, Cetkovská Petra, Vankova Radka, Krejsek Jan

机构信息

Department of Dermatology and Venereology, Faculty Hospital and Medical Faculty of Charles University, Hradec Králové, Czech Republic.

Medical Biophysic, Medical Faculty of Charles University, Hradec Králové, Czech Republic.

出版信息

Indian J Dermatol. 2020 Mar-Apr;65(2):97-104. doi: 10.4103/ijd.IJD_403_18.

Abstract

BACKGROUND

Seafood allergy is among one of the common food allergies. Decrease in consumption of omega-3 polyunsaturated fatty acids (PUFAs), prevalent especially in oily fish, has been proposed to contribute to the increased prevalence of allergic diseases.

AIM

The aim of this study was to evaluate, in atopic dermatitis (AD) patients, the relation between the occurrence of food hypersensitivity reaction (FHR) to seafish and the occurrence of other atopic diseases and parameters.

METHODS

Complete dermatological and allergological examination was performed in patients included in the study; 332 patients were examined, with the average age 26.8 years (SD 9.2 years).

RESULTS

The FHR to seafish was confirmed in 11% of patients. Patients suffering from FHR to seafish suffered significantly more from sensitization to fungi (in 46%), from reactions to celery (in 34%), and from persistent eczematic lesions (in 82%).

CONCLUSION

FHRs to seafish in AD patients are associated with persistent eczematic lesions and with the higher occurrence of sensitization to fungi and reactions to celery. The occurrence of bronchial asthma, rhinitis, positive family history, and onset of AD under 5 years of age is higher in patients with reactions to seafish, but the difference is not statistically significant.

摘要

背景

海鲜过敏是常见的食物过敏之一。有人提出,ω-3多不饱和脂肪酸(PUFA)的摄入量减少,尤其是在油性鱼类中普遍存在的ω-3多不饱和脂肪酸,可能导致过敏性疾病患病率上升。

目的

本研究旨在评估特应性皮炎(AD)患者中,对海鱼发生食物过敏反应(FHR)与其他特应性疾病及参数之间的关系。

方法

对纳入研究的患者进行全面的皮肤科和过敏科检查;共检查了332例患者,平均年龄26.8岁(标准差9.2岁)。

结果

11%的患者确诊对海鱼发生FHR。对海鱼发生FHR的患者对真菌致敏(46%)、对芹菜过敏反应(34%)以及持续性湿疹病变(82%)的发生率显著更高。

结论

AD患者对海鱼的FHR与持续性湿疹病变以及对真菌致敏和对芹菜过敏反应的较高发生率相关。对海鱼有反应的患者中,支气管哮喘、鼻炎、阳性家族史以及5岁以下AD发病的发生率更高,但差异无统计学意义。

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