• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

队列简介:韩国国家健康保险服务-国家健康筛查队列(NHIS-HEALS)。

Cohort profile: the National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS) in Korea.

机构信息

National Health Insurance Service, Wonju, Korea.

Big Data Steering Department, National Health Insurance Service, Wonju, Korea.

出版信息

BMJ Open. 2017 Sep 24;7(9):e016640. doi: 10.1136/bmjopen-2017-016640.

DOI:10.1136/bmjopen-2017-016640
PMID:28947447
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5623538/
Abstract

PURPOSE

The National Health Insurance Service-Health Screening Cohort (NHIS-HEALS) is a cohort of participants who participated in health screening programmes provided by the NHIS in the Republic of Korea. The NHIS constructed the NHIS-HEALS cohort database in 2015. The purpose of this cohort is to offer relevant and useful data for health researchers, especially in the field of non-communicable diseases and health risk factors, and policy-maker.

PARTICIPANTS

To construct the NHIS-HEALS database, a sample cohort was first selected from the 2002 and 2003 health screening participants, who were aged between 40 and 79 in 2002 and followed up through 2013. This cohort included 514 866 health screening participants who comprised a random selection of 10% of all health screening participants in 2002 and 2003.

FINDINGS TO DATE

The age-standardised prevalence of anaemia, diabetes mellitus, hypertension, obesity, hypercholesterolaemia and abnormal urine protein were 9.8%, 8.2%, 35.6%, 2.7%, 14.2% and 2.0%, respectively. The age-standardised mortality rate for the first 2 years (through 2004) was 442.0 per 100 000 person-years, while the rate for 10 years (through 2012) was 865.9 per 100 000 person-years. The most common cause of death was malignant neoplasm in both sexes (364.1 per 100 000 person-years for men, 128.3 per 100 000 person-years for women).

FUTURE PLANS

This database can be used to study the risk factors of non-communicable diseases and dental health problems, which are important health issues that have not yet been fully investigated. The cohort will be maintained and continuously updated by the NHIS.

摘要

目的

国家健康保险服务-健康筛查队列(NHIS-HEALS)是由韩国国民健康保险服务(NHIS)提供的健康筛查计划的参与者队列。NHIS 于 2015 年构建了 NHIS-HEALS 队列数据库。该队列的目的是为健康研究人员,特别是在非传染性疾病和健康风险因素以及政策制定者领域,提供相关和有用的数据。

参与者

为了构建 NHIS-HEALS 数据库,首先从 2002 年和 2003 年的健康筛查参与者中选择一个样本队列,他们在 2002 年的年龄在 40 至 79 岁之间,并在 2013 年进行了随访。该队列包括 514866 名健康筛查参与者,他们是 2002 年和 2003 年所有健康筛查参与者的随机选择的 10%。

迄今为止的发现

贫血、糖尿病、高血压、肥胖、高胆固醇血症和异常尿蛋白的年龄标准化患病率分别为 9.8%、8.2%、35.6%、2.7%、14.2%和 2.0%。前 2 年(截至 2004 年)的年龄标准化死亡率为每 10 万人 442.0 人,而 10 年(截至 2012 年)的死亡率为每 10 万人 865.9 人。两性中最常见的死因是恶性肿瘤(男性每 10 万人 364.1 人,女性每 10 万人 128.3 人)。

未来计划

该数据库可用于研究非传染性疾病和口腔健康问题的风险因素,这些都是尚未充分研究的重要健康问题。NHIS 将维护和不断更新该队列。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fb/5623538/fdd8068dc90a/bmjopen-2017-016640f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fb/5623538/58c0fbe0109e/bmjopen-2017-016640f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fb/5623538/fdd8068dc90a/bmjopen-2017-016640f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fb/5623538/58c0fbe0109e/bmjopen-2017-016640f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32fb/5623538/fdd8068dc90a/bmjopen-2017-016640f02.jpg

相似文献

1
Cohort profile: the National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS) in Korea.队列简介:韩国国家健康保险服务-国家健康筛查队列(NHIS-HEALS)。
BMJ Open. 2017 Sep 24;7(9):e016640. doi: 10.1136/bmjopen-2017-016640.
2
Cohort Profile: National health insurance service-senior (NHIS-senior) cohort in Korea.队列资料简介:韩国国民健康保险服务-老年人队列(NHIS-老年人)。
BMJ Open. 2019 Jul 9;9(7):e024344. doi: 10.1136/bmjopen-2018-024344.
3
The Multi-Institutional Health Screening Records Database of South Korea: Description and Evaluation of Its Characteristics.韩国多机构健康筛查记录数据库:描述与特征评估。
Yonsei Med J. 2019 Dec;60(12):1216-1222. doi: 10.3349/ymj.2019.60.12.1216.
4
Statin use increased new-onset diabetes in hypercholesterolemic individuals: Data from the Korean National Health Insurance Service-National Health Screening Cohort database (NHIS-HEALS).辛伐他汀的使用增加了高胆固醇血症患者新发糖尿病的风险:来自韩国国家健康保险服务-国家健康筛查队列数据库(NHIS-HEALS)的数据。
Prim Care Diabetes. 2020 Jun;14(3):246-253. doi: 10.1016/j.pcd.2019.08.005. Epub 2019 Sep 20.
5
Diabetes, Frequency of Exercise, and Mortality Over 12 Years: Analysis of the National Health Insurance Service-Health Screening (NHIS-HEALS) Database.糖尿病、运动频率与 12 年死亡率:国家健康保险服务-健康筛查数据库分析。
J Korean Med Sci. 2018 Feb 19;33(8):e60. doi: 10.3346/jkms.2018.33.e60.
6
Sex differences in the association between asthma incidence and modifiable risk factors in Korean middle-aged and older adults: NHIS-HEALS 10-year cohort.韩国中老年人群哮喘发病率与可改变风险因素的相关性存在性别差异:NHIS-HEALS 10 年队列研究。
BMC Pulm Med. 2019 Dec 16;19(1):248. doi: 10.1186/s12890-019-1023-3.
7
Association between disability and cardiovascular event and mortality: A nationwide representative longitudinal study in Korea.残疾与心血管事件和死亡的关联:韩国全国代表性纵向研究。
PLoS One. 2020 Jul 30;15(7):e0236665. doi: 10.1371/journal.pone.0236665. eCollection 2020.
8
Sex-specific Associations Between Serum Hemoglobin Levels and the Risk of Cause-specific Death in Korea Using the National Health Insurance Service-National Health Screening Cohort (NHIS HEALS).利用韩国国民健康保险服务-国民健康筛查队列(NHIS HEALS)研究血清血红蛋白水平与特定病因死亡风险之间的性别特异性关联。
J Prev Med Public Health. 2019 Nov;52(6):393-404. doi: 10.3961/jpmph.19.146. Epub 2019 Nov 1.
9
Socio-demographic factors and lifestyle associated with symptomatic hemorrhoids: Big data analysis using the National Health insurance Service-National Health screening cohort (NHIS-HEALS) database in Korea.与症状性痔疮相关的社会人口统计学因素和生活方式:使用韩国国民健康保险服务-国民健康筛查队列(NHIS-HEALS)数据库的大数据分析
Asian J Surg. 2022 Jan;45(1):353-359. doi: 10.1016/j.asjsur.2021.06.020. Epub 2021 Jun 26.
10
Disparities in cause-specific mortality by health insurance type and premium: evidence from Korean NHIS-HEALS cohort study, 2002-2019.按健康保险类型和保费划分的特定病因死亡率差异:来自韩国国民健康保险服务-健康评估与纵向研究队列(2002 - 2019年)的证据
BMC Public Health. 2024 Jun 12;24(1):1577. doi: 10.1186/s12889-024-19088-3.

引用本文的文献

1
Association between alpha-lipoic acid use and macrovascular complications in patients with diabetic neuropathy.糖尿病性神经病变患者使用α-硫辛酸与大血管并发症之间的关联
Endocrine. 2025 Sep 16. doi: 10.1007/s12020-025-04424-3.
2
The Association Between Head Trauma and BPPV: A Nested Case-Control Study Using a National Health Screening Cohort.头部创伤与良性阵发性位置性眩晕之间的关联:一项基于全国健康筛查队列的巢式病例对照研究。
Diagnostics (Basel). 2025 Aug 27;15(17):2171. doi: 10.3390/diagnostics15172171.
3
Nilotinib and imatinib: potential candidates for treatment of dementia and Parkinson's disease through national health insurance data.

本文引用的文献

1
Data Resource Profile: The National Health Information Database of the National Health Insurance Service in South Korea.数据资源简介:韩国国民健康保险服务的国家健康信息数据库
Int J Epidemiol. 2017 Jun 1;46(3):799-800. doi: 10.1093/ije/dyw253.
2
Cohort Profile: The National Health Insurance Service-National Sample Cohort (NHIS-NSC), South Korea.队列简介:韩国国民健康保险服务国家样本队列(NHIS-NSC)
Int J Epidemiol. 2017 Apr 1;46(2):e15. doi: 10.1093/ije/dyv319.
3
Hazard Ratio of Smoking on Lung Cancer in Korea According to Histological Type and Gender.
尼洛替尼和伊马替尼:通过国家医保数据看治疗痴呆症和帕金森病的潜在候选药物
Front Neurol. 2025 Aug 26;16:1628876. doi: 10.3389/fneur.2025.1628876. eCollection 2025.
4
Recent Changes in Trends of Nationwide Incidence of Glaucoma and Associated Visual Impairment in South Korea.韩国全国青光眼发病率及相关视力损害趋势的近期变化
J Clin Med. 2025 Aug 12;14(16):5691. doi: 10.3390/jcm14165691.
5
Subgroup-Specific Osteoporosis Risk in Chronic Kidney Disease: Insights from a Nationwide Korean Cohort.慢性肾脏病中特定亚组的骨质疏松风险:来自韩国全国队列的见解
Biomedicines. 2025 Aug 11;13(8):1956. doi: 10.3390/biomedicines13081956.
6
Changes in physical activity before and after the diagnosis of dyslipidemia and the risk of atrial fibrillation: a population-based study in South Korea.血脂异常诊断前后的体力活动变化与心房颤动风险:一项基于韩国人群的研究。
Prev Med Rep. 2025 Aug 8;57:103200. doi: 10.1016/j.pmedr.2025.103200. eCollection 2025 Sep.
7
Risks of cataract surgery in solid and hematologic cancer survivors.实体癌和血液系统癌症幸存者白内障手术的风险
Sci Rep. 2025 Aug 18;15(1):30263. doi: 10.1038/s41598-025-16229-5.
8
New Onset of Hair Loss Disorders During the Coronavirus Disease 2019 Pandemic: A Korean Nationwide Population-Based Study.2019年冠状病毒病大流行期间脱发疾病的新发情况:一项基于韩国全国人口的研究。
Ann Dermatol. 2025 Aug;37(4):250-258. doi: 10.5021/ad.25.007.
9
Associations Between Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Outcomes in Patients Undergoing Dialysis: A Nationwide Cohort Study.透析患者低密度脂蛋白胆固醇水平与心血管结局的关联:一项全国性队列研究
J Clin Med. 2025 Jul 8;14(14):4845. doi: 10.3390/jcm14144845.
10
Reduced cardiovascular events through dynamic lifestyle modification in individuals with prediabetes or prehypertension in Korea: a nationwide cohort study.韩国通过动态生活方式改变降低糖尿病前期或高血压前期个体的心血管事件:一项全国队列研究
Ewha Med J. 2024 Oct;47(4):e60. doi: 10.12771/emj.2024.e60. Epub 2024 Oct 31.
韩国按组织学类型和性别划分的吸烟对肺癌的风险比。
Lung. 2016 Apr;194(2):281-9. doi: 10.1007/s00408-015-9836-1. Epub 2015 Dec 31.
4
Body Mass Index and Mortality in the General Population and in Subjects with Chronic Disease in Korea: A Nationwide Cohort Study (2002-2010).韩国普通人群及慢性病患者的体重指数与死亡率:一项全国性队列研究(2002 - 2010年)
PLoS One. 2015 Oct 13;10(10):e0139924. doi: 10.1371/journal.pone.0139924. eCollection 2015.
5
Age-related differences in diabetes care outcomes in Korea: a retrospective cohort study.韩国糖尿病护理结果的年龄差异:一项回顾性队列研究。
BMC Geriatr. 2014 Oct 16;14:111. doi: 10.1186/1471-2318-14-111.
6
Association of systolic and diastolic blood pressure and all cause mortality in people with newly diagnosed type 2 diabetes: retrospective cohort study.新诊断 2 型糖尿病患者的收缩压和舒张压与全因死亡率的关系:回顾性队列研究。
BMJ. 2012 Aug 30;345:e5567. doi: 10.1136/bmj.e5567.
7
National screening program for transitional ages in Korea: a new screening for strengthening primary prevention and follow-up care.韩国的过渡期国家筛查计划:加强初级预防和随访护理的新筛查。
J Korean Med Sci. 2012 May;27 Suppl(Suppl):S70-5. doi: 10.3346/jkms.2012.27.S.S70. Epub 2012 May 18.
8
Physical activity and body mass index and their associations with the development of type 2 diabetes in korean men.体力活动和体重指数及其与韩国男性 2 型糖尿病发病的关系。
Am J Epidemiol. 2012 Jul 1;176(1):43-51. doi: 10.1093/aje/kwr471. Epub 2012 Apr 29.
9
Total cholesterol and cancer risk in a large prospective study in Korea.在韩国的一项大型前瞻性研究中总胆固醇与癌症风险。
J Clin Oncol. 2011 Apr 20;29(12):1592-8. doi: 10.1200/JCO.2010.31.5200. Epub 2011 Mar 21.
10
Newly diagnosed diabetes mellitus as a risk factor for serious liver disease.新诊断的糖尿病为严重肝病的一个危险因素。
CMAJ. 2010 Aug 10;182(11):E526-31. doi: 10.1503/cmaj.092144. Epub 2010 Jun 21.