Rodriguez-Sains R S, Robins P, Smith B, Bosniak S L
Department of Ophthalmology, Manhattan Eye, Ear and Throat Hospital, New York.
Br J Ophthalmol. 1988 Feb;72(2):134-8. doi: 10.1136/bjo.72.2.134.
Basal cell carcinomas of the eyelids, especially those in the medial canthal area, may cause extensive local destruction. Recurrent tumours are more aggressive and become progressively more difficult to treat; this is especially true for postirradiated recurrent, medial canthal, basal cell carcinomas. Tumours in this area should thus be treated by a technique which allows tissue sampling in order to gauge the adequacy of the treatment, with the goal being complete extirpation of the tumour. Excision monitored by frozen section control or Mohs' surgery is our recommendation based on a retrospective analyses of 631 eyelid basal cell carcinomas, half of which were primary tumours and half recurrent.
眼睑基底细胞癌,尤其是内眦部的基底细胞癌,可导致广泛的局部破坏。复发性肿瘤更具侵袭性,治疗难度也越来越大;对于放疗后复发的内眦部基底细胞癌来说尤其如此。因此,该区域的肿瘤应采用一种能够进行组织取样的技术进行治疗,以便评估治疗的充分性,目标是彻底切除肿瘤。根据对631例眼睑基底细胞癌的回顾性分析,我们建议采用冰冻切片控制监测下的切除术或莫氏手术,其中一半为原发性肿瘤,一半为复发性肿瘤。