Morley M, Finger P T, Perlin M, Weiselberg L R, DeBlasio D S
Department of Ophthalmology, Manhattan Eye, Ear, and Throat Hospital, New York City.
Br J Ophthalmol. 1991 Jul;75(7):407-10. doi: 10.1136/bjo.75.7.407.
We have used intravenous cis-platinum chemotherapy in the treatment of three patients with basal cell carcinoma of the lid extending into the orbit. Cis-platinum chemotherapy caused a reduction in tumour size and thereby delayed surgery in all cases. It allowed for local resection in one case, appeared to delay a patient's exenteration in a second case, and was used prior to radiotherapy in a third case. While not curative, cis-platinum may be useful as an adjuvant to decrease tumour mass prior to local excision and for patients who refuse or must delay exenteration.
我们使用静脉注射顺铂化疗来治疗3例睑部基底细胞癌累及眼眶的患者。顺铂化疗使所有病例的肿瘤大小缩小，从而延迟了手术。它使得1例患者能够进行局部切除，在第2例患者中似乎推迟了眶内容剜除术，在第3例患者中于放疗前使用。虽然顺铂不能治愈疾病，但它作为一种辅助手段，在局部切除前减小肿瘤体积以及对于拒绝或必须推迟眶内容剜除术的患者可能是有用的。
