Zheng Julia Z, Li Yangyi, Lin Tuo, Estrada Angelica, Lu Xiang, Feng Changyong
Department of Immunology and Microbiology, McGill University, Montreal, Canada.
Department of Mathematics, State University of New York in Stony Brook, Stony Brook, NY, USA.
Shanghai Arch Psychiatry. 2017 Aug 25;29(4):250-256. doi: 10.11919/j.issn.1002-0829.217101.
Sample size justification is required for all clinical studies. However, to many biomedical and clinical researchers, power and sample size analysis seems like a magic trick of statisticians. In this note, we discuss power and sample size calculations and show that biomedical and clinical investigators play a significant role in making such analyses possible and meaningful. Thus, power analysis is really an interactive process and scientific researchers and statisticians are equal partners in the research enterprise.
所有临床研究都需要进行样本量合理性论证。然而,对于许多生物医学和临床研究人员来说,效能和样本量分析似乎是统计学家的一个魔术。在本笔记中,我们讨论效能和样本量计算,并表明生物医学和临床研究人员在使此类分析成为可能且有意义方面发挥着重要作用。因此,效能分析实际上是一个互动过程,科研人员和统计学家在研究事业中是平等的伙伴。