Rodriguez-Morales Alfonso J, Haque Ubydul, Ball Jacob, García-Loaiza Carlos Julian, Galindo-Marquez Maria Leonor, Sabogal-Roman Juan Alejandro, Marin-Loaiza Santiago, Ayala Andrés Felipe, Lozada-Riascos Carlos O, Diaz-Quijano Fredi A, Alvarado-Socarras Jorge L
Public Health and Infection Research Group, Faculty of Health Sciences, Universidad Tecnologica de Pereira, Pereira, Risaralda, Colombia; Colombian Collaborative Network on Zika and other Arboviruses (RECOLZIKA), Pereira, Colombia; Organización Latinoamericana para el Fomento de la Investigación en Salud (OLFIS), Bucaramanga, Santander, Colombia.
Department of Public Health and Prevention Science, Baldwin Wallace University, Berea, OH, USA.
Infez Med. 2017 Sep 1;25(3):241-246.
In this study, we investigated the weekly reported spatio-temporal distribution and topographic risk factors for Zika virus (ZIKV) infection in northeastern Colombia. Weekly reported surveillance data, including clinical, suspected and confirmed cases from the ongoing ZIKV epidemic in the Santander and Norte de Santander departments (Santanderes) in Colombia were used to estimate cumulative incidence rates. Spatial analysis was performed to develop hot spot maps and to identify spatial topographic risk factors for infection. From January 1, 2016 to March 19, 2016, 11,515 cases of ZIKV were reported in Santanderes, with cumulative rates of 316.07 cases/100,000 population for the region (representing 18.5% of the cases of the country). Five municipalities (four in Norte de Santander) reported high incidence of ZIKV infection (>1,000 cases/100,000 pop); these municipalities are close to the border with Venezuela. Most of the cases reported occurred mainly in low altitude areas, and persistent hot spots were observed. Higher infection rates were reported in the Northeastern part of the study area. Use of risk maps can help guide decisions for the prevention and control of ZIKV. Hotspots on the Colombia-Venezuela border can have implications for international spread.
在本研究中，我们调查了哥伦比亚东北部地区寨卡病毒（ZIKV）感染的每周报告的时空分布及地形危险因素。利用来自哥伦比亚桑坦德省和北桑坦德省（桑坦德雷斯地区）正在流行的寨卡病毒疫情的每周报告监测数据，包括临床病例、疑似病例和确诊病例，来估计累积发病率。进行空间分析以绘制热点地图，并确定感染的空间地形危险因素。2016年1月1日至2016年3月19日，桑坦德雷斯地区报告了11515例寨卡病毒病例，该地区的累积发病率为每10万人口316.07例（占该国病例数的18.5%）。五个市（北桑坦德省的四个市）报告了寨卡病毒感染的高发病率（>每10万人口1000例）；这些市靠近与委内瑞拉的边境。报告的大多数病例主要发生在低海拔地区，并观察到持续的热点区域。研究区域东北部的感染率较高。使用风险地图有助于指导寨卡病毒防控决策。哥伦比亚 - 委内瑞拉边境的热点地区可能对国际传播产生影响。
